2024 College Football Week 12 Odds and Predictions

Somehow, we blinked and it’s Week 12 of the 2024 college football season. What a season it has been and there is still plenty of football left to play. The first College Football Playoff rankings came out last week and there weren’t many surprises. That poll will change as two of the top four teams in the country lost in Week 11. No. 2 Georgia fell 28-10 to Ole Miss while fourth-ranked Miami was upset by Georgia Tech 28-23.

It’s only going to get crazier as we approach the end of the regular season and the coming conference championship games. There is only one matchup of ranked opponents this week. That means there is some serious potential for some big upsets. No. 6 Tennessee travels to Athens to take on No. 6 Georgia. After last week’s loss to Ole Miss, the Bulldogs can’t afford another loss.

Each conference race is heating up. Earning a shot at a conference title will mean a shot at the College Football Playoff. For some conferences – the ACC, for example – the conference champ is likely the only member playing for a national title. Miami fell victim to the upset last week, dropping a 28-23 decision to Georgia Tech. SMU (9-1, 5-0) is the only remaining unbeaten in the ACC. The Mustangs play Boston College this week and finish the season with Virginia and California. Miami and Clemson each have one loss. The end of the regular season should be a wild ride.

The ride could be the wildest in the SEC where the Tennessee-Georgia game is the week’s big game. Scores & Stats has all the latest on this game as well as the rest of the Week 12 schedule. Our experts will help you through the end of the regular season and all the way through to the 2024-25 College Football Playoff national championship. It’s hard to believe, but we have just four weeks of the regular season left. Let’s take a look at this week’s odds.

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College Football Week 12 Odds

Keep an eye on the latest College Football Odds and monitor how the lines change throughout the week.

The Tennessee-Georgia game that we mentioned will help clear up some of the congestion at the top of the SEC. Nine teams from the conference are ranked in the CFP poll with Texas A&M, Tennessee, and Texas all with one loss. Georgia is among five more SEC teams with two losses. A Bulldogs loss effectively removes them from both the conference and CFP races.

A Vols win moves them one step closer to the SEC title game. Texas is at Arkansas on Saturday while Texas A&M has a non-conference game against New Mexico State (2-7). One of the two, the Longhorns or Aggies, will have another loss. The old Texas-Texas A&M rivalry rekindles this year in the final week of the regular season. There’s still a lot of football left and circumstances could change, but another loss hurts any of these teams at the top of the SEC.

At this point in the season, there aren’t a ton of mismatches like those we saw early in the season. There is the Texas A&M-New Mexico State matchup. The Aggies are favored by 39 points. Penn State and Ohio State are both 28.5-point favorites against Purdue and Northwestern, respectively. Other than those, there aren’t many double-digit favorites in Week 12.

Last week, we mentioned there have been more than 150 games with a total of 60 or higher this season. Around 62 percent of those games have gone Under. This week, there is one game with a total higher than 70. New Mexico hosts No. 21 Washington State on Saturday night. The game total has been set at 72.5.

Our Scores & Stats experts were on their game last week. S&S experts hit 12 of 21 predictions, including last week’s college football parlay. Duke beat NC State as a 3.5-point underdog and Marshall covered as a 13.5-point favorite over Southern Miss. Those who bet $100 on that parlay profited $250. Let’s see if our guys can do it again in Week 12.

College Football Week 12 Schedule

With over 65 College Football games scheduled for Week 12, the following is a list of the featured games of the week:

College Football Week 12 Predictions

Let’s take a look at the featured College Football Week 12 games and make our spread, total, and moneyline NCAAF picks for each game.

Clemson Tigers vs. Pittsburgh Panthers Odds

Clemson had won six straight before an upset loss to Louisville. The Tigers then rebounded last week with a 24-14 win over Virginia Tech. Clemson has only covered two of its last five games and the Tigers are just 4-4 ATS for the season. They are, however, 5-1 ATS in their last six games in November. Staying hot in November is crucial for Clemson is they hope to earn a College Football Playoff berth.

Pittsburgh opened the 2024 season with seven straight wins. Now, heading into Week 12, the Panthers have lost two straight. They got blown out by SMU in Dallas then suffered a 24-19 upset loss to Virginia last week. Now with two losses in ACC play, the Panthers are likely out of the conference title picture.

With the two losses, Pitt is now just 1-3 ATS in its last four games. For the season, Pitt is 6-3 ATS. They have done well playing at home where they are 6-1 SU in their last seven games. Unlike Clemson, the Panthers have not done well late in the season. Pitt is just 1-5 SU in its last six games played in November.

Clemson and Pitt have played four times since 2016. The two teams have split the four games. Pitt won the last meeting 27-17 in 2021. Two games have gone Over the total and two have gone Under. Clemson averages 42 points per game. Pitt averages 40.9. Both teams are among the most prolific in the country. There are some questions though about Pit QB Eli Holstein. He’s listed as probable after suffering a head injury.

Clemson Tigers vs. Pittsburgh Panthers Predictions

With Holstein not 100 percent, the Panthers offense has struggled. As mentioned, the Panthers average over 40 points per game. However, over the past four games, Pitt has scored 25 points or fewer in three of them. Part of the problem is Holstein and if he is not sharp on Saturday, this could get ugly.

Clemson head coach Dabo Swinney is solid in revenge games. Pitt won the last game against the Tigers. Swinney is 32-14 SU against a team that he lost to in his last matchup. Swinney’s Tigers are also 6-0 SU and ATS as a double-digit favorite on a road trip (second game of the trip or later).

The Tigers are also 4-1 SU in their last five games and they are 8-4 ATS in their last 12 games as a favorite. Clemson still is in the running for a berth in the ACC title game. The Panthers already have two losses and seem to be eliminated from playoff contention. Four of Pitt’s last five games have gone Under the total, but six of their last eight as an underdog have gone Over the total. With the status of Holstein up in the air, Clemson should win this one, but the Panthers, playing at home, can keep it close.

Bet: Clemson ML, Pitt +10 (-110), Over 54 (-110)

Utah Utes vs. Colorado Buffaloes Odds

The No. 20 team in the country, Colorado, plays the host to Utah this Saturday. The Utes season hasn’t gone according to plan. Utah opened the season with four straight wins but has now lost five in a row since. The difference, of course, is not having QB Cam Rising in the lineup. The seventh-year quarterback willed the Utes to wins over his career in Salt Lake City. Without him, the offense has been mostly non-existent.

The Utes failed to cover the first four of their losses before covering last week in the Holy War battle against BYU. Utah’s defense, which ranks 11th in the nation in points allowed per game (16.5), is keeping the Utes in games. That defense will have its hands full on Saturday afternoon.

The Buffaloes were kind of written off after an early season loss to Nebraska. Colorado later lost by three points to a ranked Kansas State. Coach Prime and his Buffs are now 7-2 and 5-1 in Big 12 play. They have a clear path to the Big 12 title game where a win would put the Buffaloes in the College Football Playoff. First, they will have to get by Utah.

It’s hard to imagine Utah keeping up with the Colorado offense. The Buffaloes average 31.4 points per game. What many fail to realize is the Colorado defense is pretty good. That’s why the Buffaloes are +10.5 in scoring margin. Colorado is 6-1 SU in its last seven games and 7-0 ATS.

Utah has won nine of the last ten games in the series. The Utes have covered six of the last eight against Colorado. The Under has cashed in five of Utah’s last six games and in four of the last six against Colorado. The Over is 3-0-1 in Colorado’s last four home games.

Utah Utes vs. Colorado Buffaloes Predictions

The Colorado Buffaloes are currently in second place in the Big 12 and have won six of their last seven games. It’s not impossible that Colorado could end up in a conference championship game with a chance to earn a postseason berth, especially with three games left.

For CFB bettors, the Buffaloes have been even more profitable. In its last seven games, Colorado has a 7-0 ATS record, including four covers as a favorite. Five times, including in their last three Big 12 games, the Buffaloes have won by double digits.

As mentioned, the Utes have lost five in a row. In each of those games, they have lost by 13 points or less, and in the last three, they have lost by a single score. The Utes’ heartbreaking loss to the BYU Cougars last week, in which they had a controversial defensive holding penalty and then gave up a game-winning field goal, was the best example of this trend.

We are all aware by now of Colorado’s proficiency with the passing game. In addition to Travis Hunter and LaJohntay Wester, Shedeur Sanders has thrown for 24 touchdowns. Behind those two is a strong group of wide receivers.

The Colorado defense has also made great strides, averaging 3.2 sacks per game and giving up just 22.6 points per game. The Utah offense, which hasn’t scored more than 21 points in a game since mid-September, will have serious trouble with that.

Colorado is scoring an average of 32.6 points per game. The Over is 4-1-1 over the Buffaloes’ last six games, and while the Colorado defense is definitely better than it was the previous season, it is still far from great. Nevertheless, Colorado has a strong defensive record overall, holding four of its previous five opponents to 27 points or less.

Bet: Colorado -400, Utah +10.5 (-110), Over 47.5 (-110)

LSU Tigers vs. Florida Gators Odds

It’s another SEC battle when LSU travels to Gainesville. The Tigers are still in the thick of the SEC race though another loss would all but ruin their chances at both a conference title and a spot in the CFP. Florida, like LSU, has lost two straight and is now 4-4. The Gators earlier in the week decided they would stick with head coach Billy Napier despite his 16-18 overall record in two-plus seasons.

Historically, LSU has been in command of this rivalry. The Tigers have won eight of the last ten games against the Gators and many of those wins have been of the high-scoring variety. LSU won last year 52-35, covering as a 16.5-point favorite. The game went way Over the total of 68. Are we in for more of the same this season?

Both teams do average over 30 points per game. LSU scores 32.8 and Florida averages 30.9. The defenses are also comparable. Both teams give up an average of around 23 points a game. The difference is probably at the quarterback position. LSU’s Garrett Nussmeier is having an outstanding season. Florida lost starter Graham Mertz to injury. The Gators turned to freshman D.J. Lagway, but he was injured in the loss to Georgia. Last week, Florida went with another freshman, Aidan Warner.

LSU is just 3-5 ATS this season, 3-7 ATS in its last 10 games. Florida, as mentioned, is 4-5 SU but 5-3 ATS against FBS teams. The Gators have covered in five of their last six games. The Over has cashed in five of Florida’s eight games this season and in 13 of their last 17. The Over is 7-1 in LSU’s last eight road games and the last six meetings between these two teams have seen the Over cash each time.

LSU Tigers vs. Florida Gators Predictions

After a 29-point loss at home to Alabama, the Tigers are currently on a two-game losing streak and are ranked 15th in the country. As mentioned, Nussmeier leads LSU’s offense with 2,866 yards and 21 touchdowns on 235 completions. Kaden Durham leads the team with 460 rushing yards and six touchdowns on 81 carries. With 46 receptions, Kyren Lacy is the leading receiver with 697 yards and seven touchdowns.

After losing to Texas by 32 points on the road in their most recent game, the Florida Gators enter this week with just four wins in their nine games this season. Florida’s offense has been strong this season, averaging just over 31 points and over 400 yards per game, but the Gators’ defense is extremely mediocre.

The loss a week ago leaves LSU with a bitter taste in its mouth. The Gators enter this game on a low note after two straight losses. Keep in mind, the Tigers have won each of the last five against Florida and they are 4-0-1 ATS in those five games. In games with two teams that average more than the game total, the Under cashes roughly 58 percent of the time.

Bet: LSU -178, LSU -4.5 (-110), Under 55.5 (-110)

Boston College Eagles vs. SMU Mustangs Odds

SMU is the last remaining team that is unbeaten in ACC play. It could be the Mustangs that represent the ACC in the College Football Playoff in their first year in the conference. They will have to get past Boston College first. The Eagles (5-4) have some issues at the quarterback position to work out.

This will be the first meeting between the two teams as members of the ACC. Ironically, the only time the two schools have met in the modern era was just last year. The two played each other in the 2023 Fenway Bowl. Boston College won the game 23-14. BC QB Thomas Castellanos threw for 102 yards and ran for 155 more and two touchdowns.

One of the big differences heading into Saturday’s game is that Castellanos, a junior, will not be under center. He was benched last week by head coach Bill O’Brien and it appears that the former Eagles starting quarterback will enter the transfer portal. Grayson James will start for Boston College.

Boston College is 2-3 in conference play. The Eagles lost three straight, all in conference, before beating Syracuse 37-31 last week. James finished the game for BC and went 5-of-6 for 51 yards and a touchdown. Boston College has not been good against the number though. The Eagles are 2-4 ATS in their last six games.

On the other side, SMU has won six straight, five in ACC play. The Mustangs are 5-1 ATS in those six games. They are also 12-1 SU in their last 13 games at home. All SMU has to do to make their first ACC championship game is beat BC on Saturday and then take care of two 5-4 teams, Virginia and California.

Boston College Eagles vs. SMU Mustangs Predictions

SMU is ranked No. 14 and is 8-1 on the season. The Mustangs have a 4-1 home field record this season. SMU scores 40.1 points and averages 453 yards per game. In their most recent game, the Mustangs defeated Pittsburgh 48–25. Two of SMU’s last three games have seen them score at least 40 points.

Boston College has struggled on the road this season going 1-3. The Eagles are scoring 27.6 points and gaining 366 yards per game on average. BC has a pretty good run defense, ranking in the top 50, giving up 129 yards per game. The problem is the pass defense. The Eagles rank in the bottom 20 in the FBS, allowing over 264 passing yards per game.

Without Castellanos at quarterback, BC will not have that experienced dual-threat option. They will, however, have Kye Robichaux at running back. Last week, he ran for 198 yards on 28 carries in the win over Syracuse. The Mustangs are a top 50 defense though and that’s one of the reasons why they are 6-3 ATS this season.

With home field advantage, SMU is the unquestionably superior team, but this might be too many points here. Look for O’Brien to have the Eagles ready to go and to keep this one with three scores.

Bet: ML pass, BC +17.5 (-110), Over 53.5 (-110)

Tennessee Volunteers vs. Georgia Bulldogs Odds

In Week 12 of the college football season, the Georgia Bulldogs are surprisingly big home favorites over the Tennessee Volunteers. The Bulldogs are coming off a huge 28-10 loss to Ole Miss last week. That loss does some serious damage to Georgia’s hopes of an SEC title and a spot in the 12-team playoff.

Tennessee is one of two teams (Texas A&M is the other) in the SEC with one loss. The Vols can continue their quest toward a conference title game berth with what would be a huge win over the Bulldogs. Georgia won last year’s game 38-10 and has won eight of the last ten against the Vols, including the last seven in a row. The Bulldogs are 5-0 ATS in the last five against Tennessee.

Neither team has had much success against the spread recently. Georgia is actually 1-7 ATS in its last eight games. Tennessee has covered just once in its last five. The Vols have been an underdog just one other time this season. That was against Alabama on Oct. 19. Tennessee won the game outright 24-17. Underdogs in the SEC this year are 32-15-1 ATS, which is the best mark of any conference. Road underdogs do even better. They are 17-4-1 ATS in conference games.

Both defenses are among the top 20 in the country in terms of scoring. For all the press its offense gets, Tennessee’s defense ranks fifth in the nation allowing 13.8 points per game. The Under has been in play for both teams all season. Five of the last six Tennessee games and 9 of Georgia’s last 13 have gone Under the total.

Tennessee Volunteers vs. Georgia Bulldogs Predictions

This game likely comes down to which quarterback fares better against the opposing defense. Both defenses, as mentioned, can get after it. Georgia QB Carson Beck has struggled this season after being a preseason Heisman Trophy favorite.

Last week, Beck threw for 186 yards and one interception. He also fumbled twice, which killed the Bulldogs. This season, Beck has thrown a total of 12 interceptions, which is tied for the most in the FBS. Nine of those picks have come in Georgia’s last four games. One of the keys for Georgia will be offensive tackles Xavier Truss and Earnest Greene. If those two can’t find a way to neutralize Vols edge rusher James Pearce, Beck is in for a long night.

Georgia’s defense will have to come up big and stop the Tennessee run game. The Bulldogs rank 17th in run defense and will go up against a Vols run game that averages 226.8 yards per game (8th in FBS). How that plays out as well as how Tennessee QB Nico Iamaleava plays will determine the Vols fate. Iamaleava went out of last week’s game with an upper body injury. Tennessee head coach Josh Heupel is confident his quarterback will play in Week 12.

Bet: Georgia ML, Tennessee +9.5 (-110), Under 48.5 (-110)

Boise State Broncos vs. San Jose State Spartans Odds

Boise State sits right outside the CFP top 12 and No. 13. The Broncos are the highest-ranked Group of 5 team and have a clear path to the playoffs. In Week 12, Boise State will try and avoid the upset to San Jose State, a team that is 6-3 and could give the Broncos some issues. The Spartans passing game could keep them in this game long enough to do some damage.

The Broncos failed to cover last week against a 3-8 Nevada team. Boise State could never pull away from the Wolfpack despite 209 yards and three touchdowns from Heisman Trophy favorite Ashton Jeanty. Nevada scored a late touchdown (2:19 remaining in the game) to make the game appear closer than it was. Still, teams are going to give the Broncos their best effort in hopes of pulling the upset.

San Jose State has had a lot of recent success. The Spartans are 12-4 SU in their last 16 games dating back to former head coach Brent Brennan, now at Arizona. New head coach Ken Niumatalolo is off to a strong start. At 3-2 in Mountain West play, San Jose State is not completely out of the conference championship picture. Saturday’s game will determine whether the Spartans remain in it.

Boise State is 4-1-1 ATS in its last six games. The lone loss in that span came last week when the Broncos were 23.5-point favorites against Nevada. San Jose State has been an underdog four times this season. They are 3-1 ATS in those games. One of those covers was as a 13-point underdog to Washington State. The Spartans lost 54-52 in double overtime.

Boise State Broncos vs. San Jose State Spartans Predictions

Boise State averages 43.8 points per game this season. That ranks second in the country. The passing attack is solid with Maddux Madsen running the offense. He’s passed for 1,908 yards and 18 touchdowns. It’s the running game, though, where the Broncos really shine. They average 268.6 rushing yards per game. That is third in the nation. They are led, of course, by Jeanty, who has four 200-yard-plus games this season and 1,734 yards and 23 touchdowns.

San Jose State picked up a big win last week, beating Power 4 Oregon State 24-13. The Spartans offense isn’t as prolific as Boise State’s, averaging 29 points per game. The passing offense is very good, averaging 332.3 yards per game. The Spartans are the fifth-best passing offense in the country.

If Boise State has a chink in its armor, it’s the pass defense. The Broncos rank 113th in the nation allowing opposing offenses to throw for over 261 yards per game.  Boise’s game plan will likely be to run the football with Jeanty and keep the ball away from the Spartans pass-happy offense.

Boise State and Colorado State are the two remaining unbeatens in the Mountain West. San Jose State will likely give the Broncos all they can handle as they look to pull the upset. Boise State’s last remaining MWC game is against Wyoming next week. The Broncos will likely get the Cowboy’s best too.

Bet: ML pass, San Jose State +13.5 (-110), Under 61.5 (-110)

Kansas Jayhawks vs. BYU Cougars Odds

Kansas came into this season fresh off a 9-4 bowl season. They rolled Lindenwood in their first game then went on an 0-for-5 run in which they lost games to Illinois, UNLV, West Virginia, TCU, and Arizona State. As we look back, those five teams all have winning records and combined, they are 31-15.

Now, Kansas is 3-6 heading to undefeated BYU which is 9-0. The Cougars needed to comeback and beat rival Utah 22-21 last week. BYU has won nine straight and they are 8-1 ATS. If you go back to last season, the Cougars are 9-2 ATS in their last 11 games and 9-2 SU in their last 11 home games.

Kansas is 3-6 ATS this season, however, in their last five games played in the month of November the Jayhawks are 4-1 ATS. The Jayhawks have been known to produce some points in head coach Lance Leipold’s high-powered offense. Despite all the losses, the last six Jayhawks games have all gone Over. Four of the last five road games have also gone Over the total.

BYU is the 22nd-ranked defense in the country. They face some low totals which is why each of their last five games have gone Over the total. Each of those game totals was 53.5 or less. Last week, the game total was 40.5 as the Cougars faced the Utes, another strong defense. BYU fell behind 21-0 before Cougars QB Jake Retzlaff took over. He passed for 219 yards and had a rushing touchdown to help BYU stave off the upset.

Kansas Jayhawks vs. BYU Cougars Predictions

Kansas jumped out to a 35–13 halftime lead and held on for the victory 45–36 in last Saturday’s win over then-No. 13 Iowa State. Devin Neal carried 18 times for 116 yards and two touchdowns, while Jalon Daniels recorded 295 pass yards with two scores (including a rush touchdown).

The Jayhawks rolled up 532 yards of offense last week. They rushed for 237 against Iowa State, 192 in a near-miss against Kansas State, and over 200 against Houston. BYU was carved up by Oklahoma State for over 200 rushing yards, so it can be done.

Keep in mind that of BYU’s nine opponents only three have a winning record. Collectively, the Cougars’ opponents are 39-45 SU. Kansas does well in the underdog role. In their last four games as an underdog against AP ranked teams, Kansas has covered each time.

Kansas QB Jalon Daniels has been a different guy recently. He threw eight picks in his first six games, but he’s got eight touchdowns and just one interception in his last three games. Kansas won two of its last three and lost to rival Kansas State by two, 29-27.

One thing to keep in mind is BYU’s home record in night games. The Cougars are 31-3 in games at home that start at 6 p.m. or later. Playing at home might not be enough to fight off a red-hot Kansas team.

Bet: Kansas +125, Kansas +3.5, Over 55.5 (-110)

Best Bets for College Football Week 12

There are a number of great matchups in Week 12 of the regular season. The Scores & Stats college football staff have collectively prodded over the week’s betting board searching for value. Here are Week 12’s best bets.

• Penn State -28.5 @ Purdue
• Ohio State @ Northwestern Over 44.5

Two spot plays make up our best bets in Week 12. Penn State under James Franklin has won 23 straight games as a double-digit favorite. He’s 72-4 SU and 47-27-2 ATS in games with Penn State and Vanderbilt. The Nittany Lions are just 2-3 ATS as double-digit favorites this season.

On the road, Penn State has been tough to take down. Since 2020, the Nittany Lions are 13-3 SU and 12-4 ATS. Since 2022, they’ve been even better – 11-0 SU and 10-1 ATS.

Ohio State just doesn’t lose to Northwestern. The Buckeyes are 34-1 SU since 1972 with the only loss coming in 2014. Like Penn State under Franklin, Ohio State head coach Ryan Day is 55-1 SU and 33-22-2 ATS as a double-digit chalk.

Last week, Day and the Buckeyes shutout Purdue. Over the last two seasons, teams coming off a shutout are 40-23 SU and 36-25-2 ATS in their next game. Interestingly, 36 of those 63 games went Over the total. Since 2010, when there is a total of 46 or less and one team is favored by 30 or more, the Over is 36-8.

You’ll get -110 odds on Penn State to cover the spread and -115 odds for Ohio State-Northwestern to go Over the total. You can wager $20 on each game and if you win both bets, you’ll net a little over $35. You can also play these two bets as a parlay. One $20 wager will pay back over $51 if both bets cash.