Top Five NFL Week 10 Point Spread Picks

The 2021 NFL season heads to Week 10 with plenty of football still to play. Week 9 provided plenty of drama including a 9-6 Jacksonville upset of Buffalo. What will unfurl this week?

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Here’s a look at the top five NFL Week 10 ATS picks.

Jaguars vs. Colts Week 10 Spread

Jaguars vs. Colts Predictions

This is déjà vu all over again for the Colts. Last Thursday, the Colts were a double-digit favorite over a bad team coming off an upset win. The Jets had beaten Cincinnati the week prior. Indy then dismantled the Jets winning by 15 (45-30) and covering the spread.

Lo and behold, this week it’s the Jags coming off an improbable 9-6 upset of the Buffalo Bills. Indy is, of course, favored by 10.5 points. The Colts dominate bad football teams by running the football and playing good defense. That will happen again on Sunday.

Best ATS Pick: COLTS -10.5

NFL Point Spread Odds

Vikings vs. Chargers Week 10 Spread

Vikings vs. Chargers Prediction

The Vikings aren’t winning games, but they continue to find ways to lose but cover. They did it once again last week in a 34-31 loss to Baltimore.

This week, Minnesota is a 3-point underdog on the road at Los Angeles. The Chargers have two things working against them – a secondary ravaged by injuries and a run defense that is the NFL’s equivalent to Swiss cheese.

The secondary problem should allow Adam Thielen and Justin Jefferson to have some success in the Vikings passing. RB Dalvin Cook should run wild on the Chargers, which is why there is tremendous value on Minnesota as an underdog.

Best ATS Pick: VIKINGS +3

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Browns vs. Patriots Week 10 Spread

Browns vs. Patriots Prediction

The Patriots have won their last three straight and four of their last five games. Rookie QB Mac Jones continues to improve, but there is something to be said for the Cleveland Browns.

Last week, the Browns walloped AFC North and in-state rival Cincinnati 41-16. They did it by sticking to the plan. That plan includes running the ball with the NFL’s second-best rushing offense. It also includes not asking Baker Mayfield to do too much.

Surprisingly, the Patriots are just 1-4 at home this season. New England has one of the best home records in the NFL since it started playing at Gillette Stadium in 2002. This is a great spot for the Browns to catch New England in a letdown situation.

Best ATS Pick: BROWNS +1.5

NFL Point Spread Picks

Eagles vs. Broncos Week 10 Spread

Eagles vs. Broncos Prediction

Denver upset Dallas last week, but don’t expect another 30 points from the Broncos offense which only averages 20.8 per game. The Denver offense is more or less a dink-and-dunk passing game with Teddy Bridgewater at quarterback.

On the other end, Philly doesn’t really have a drop-back passing game with Jalen Hurts at quarterback. The Eagles are a team that relies heavily on the run. They did so last week against the Chargers gaining 176 yards on the ground. Don’t expect that against a Denver defense that allows only 98 rushing yards a game.

Good defense beats one-dimensional offense in this one. Plus, the Eagles have to play at elevation.

Best ATS Pick: BRONCOS -2.5

Chiefs vs. Raiders Week 10 Spread

Chiefs vs. Raiders Prediction

The Chiefs are 11-2 straight up and 8-5 ATS in the last 13 games against the Raiders. With a win over the Packers last week, Kansas City opened as a 2.5-point favorite over the Raiders on the road this week.

The problem with that is that the Chiefs offense has scored a total of 36 points in its last three games. The Chiefs defense has plenty of holes and the Chiefs are just 3-16-1 ATS in their last 20 games. That includes just 2-8 ATS in the last ten.

Best ATS Pick: RAIDERS +2.5

About the Author
Rick Bouch
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Rick Bouch is a former high school, college, and professional athlete who now spends his time writing about sports and sports betting. Rick has played and coached football at various levels and brings a unique perspective to sports handicapping. He is continuously on the cutting edge of all things football. While college football is his specialty, Rick’s knowledge spans all of the major sports.
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