The 2022 NFL season continues to be extremely hard to predict, as there are big upsets happening throughout the league each week. Things are going to start settling down at some point and week 6 could be a perfect time.
There are some great betting options out there when it comes to the NFL and betting against the spread remains one of those top options. Here are five of the best NFL week 6 point spread picks to make.
New York Jets at Green Bay Packers
Jets vs. Packers Prediction
Best Bet: Packers -7
A pair of 3-2 teams take the field in Green Bay, as the Packers are seven-point betting favorites at home. New York has been putting up big numbers through the air this season and they have been getting stops on defense.
Aaron Rodgers has struggled up to this point for the Packers, but he is too good to continue to struggle. This should be a great opportunity for Rodgers to take off and he will lead the Packers to a big win to cover the spread.
Jacksonville Jaguars at Indianapolis Colts
Jaguars vs. Colts Prediction
Best Bet: Colts -2
The AFC South Division is full of teams that are underperforming to begin the year. That includes the Jaguars and Colts. Indianapolis was expected to dominate this division, but they are still waiting to really get things going.
Jacksonville was a pleasant surprise through four weeks, but they struggled mightily in a loss to Houston in week 5. The Colts are scoring just 13.6 points per game, but they should be able to turn that around in this one.
Take the Colts at -2 as they pick up an important division win.
Cincinnati Bengals at New Orleans Saints
Bengals vs. Saints Prediction
Best Bet: Bengals -1.5
A pair of 2-3 NFL teams are set to meet up in New Orleans in week 6, as the Saints host the Cincinnati Bengals. It has been an intriguing start to the NFL season for each team, as the Bengals and Saints are both looking for some consistency.
The Bengals are averaging just 91 rushing yards per game. That puts too much pressure on Joe Burrow and the passing attack. New Orleans is giving up nearly 26 points per game and that defense will have to improve.
Cincinnati is the better overall team and they will win this game by at least a touchdown.
Baltimore Ravens at New York Giants
Ravens vs. Giants Prediction
Best Bet: Giants +5
The Giants are one of the biggest surprises in the NFL this season, but they are significant underdogs in week 6. New York hosts a Baltimore Ravens team that is 3-2, but they have also been prone to blowing big leads.
The Giants are averaging 179 rushing yards per game and Saquon Barkley has been terrific all season long. Baltimore is the better overall team, but they aren’t going to be able to completely take over this game.
Giving the Giants five points at home is too many and they keep this game close to cover.
Tampa Bay Buccaneers at Pittsburgh Steelers
Buccaneers vs. Steelers Prediction
Best Bet: Buccaneers -8
The Pittsburgh Steelers are an absolute mess and that’s going to be a problem with Tom Brady and the Buccaneers coming to town. Pittsburgh has turned to Kenny Pickett at the quarterback position and they just don’t have an offense that is capable of doing a lot of damage.
Injuries have plagued the Buccaneers so far this season, but this team is starting to get healthy again. Even though the Steelers are a decent defensive team, look for Tampa Bay to have a big day on offense as they win by double-digits.