NFL Week 16 Opening Lines and Odds Comparison

We’re going to analyze NFL week 16 opening lines and compare them to the current betting odds.

Top NFL Betting Sites

The NFL schedule is going to be a bit different this week due to Christmas. There will still be one game on Thursday night and Monday night. Most teams will play Saturday with three games on Sunday.

NFL Week 15 Betting Recap

Underdogs dominated in week 15. Favorites only went 6-9-1 ATS (Season Record: 97-118-7 ATS). There were four underdogs that won straight-up (Jaguars, Lions, Steelers and Giants).

The over/under record was 8-8 in week 15 (Season O/U Record: 98-121-4).

Best NFL Handicappers

Analyzing NFL Week 16 Line Movement

Every team is in action again this week. Let’s jump into the NFL week 16 betting lines.

Jacksonville Jaguars vs. New York Jets

Opening Spread: Jets -1.5 / Current Spread: Jets -1

Opening Total: 43 Points / Current Total: 39.5 Points

The Jaguars are just 2-5 ATS on the road this season, but they’re on a 2-0 (2-0 ATS) run.

Atlanta Falcons vs. Baltimore Ravens

Opening Spread: Ravens -6.5 / Current Spread: Ravens -7

Opening Total: 40.5 Points / Current Total: 39.5 Points

Lamar Jackson is questionable to play and the Ravens are 0-5-1 ATS at home this season.

New York Giants vs. Minnesota Vikings

Opening Spread: Vikings -4 / Current Spread: Vikings -3.5

Opening Total: 47.5 Points / Current Total: 47.5 Points

The Vikings are 7-1 at home, but only 4-4 ATS. The Giants are 5-1 ATS on the road this season.

New Orleans Saints vs. Cleveland Browns

Opening Spread: Browns -3 / Current Spread: Browns -3

Opening Total: 36.5 Points / Current Total: 33.5 Points

The Saints are 1-5 (1-5 ATS) on the road this season, but the Browns are tough to trust.

Buffalo Bills vs. Chicago Bears

Opening Spread: Bills -10 / Current Spread: Bills -9

Opening Total: 41 Points / Current Total: 41.5 Points

Buffalo have won five in a row, but they’re 2-6 ATS in their last eight games.

NFL Week 16 Odds

Seattle Seahawks vs. Kansas City Chiefs

Opening Spread: Chiefs -9.5 / Current Spread: Chiefs -9.5

Opening Total: 48.5 Points / Current Total: 49 Points

The Chiefs are on a 0-3 ATS run and the Seahawks are on an even worse run (0-5 ATS).

Cincinnati Bengals vs. New England Patriots

Opening Spread: Bengals -3.5 / Current Spread: Bengals -3.5

Opening Total: 41 Points / Current Total: 40 Points

The Bengals are 6-2 ATS on the road this season. The Patriots are 2-5 ATS as an underdog.

Detroit Lions vs. Carolina Panthers

Opening Spread: Lions -2.5 / Current Spread: Lions -3

Opening Total: 44.5 Points / Current Total: 44.5 Points

The Lions are on a 6-1 (7-0 ATS) run and in the middle of the NFC wild card race.

Houston Texans vs. Tennessee Titans

Opening Spread: Titans -8.5 / Current Spread: Titans -7

Opening Total: 41 Points / Current Total: 38.5 Points

The Titans are 0-4 in their last four games. The Texans are on a 2-0 ATS run.

Washington Commanders vs. San Francisco 49ers

Opening Spread: 49ers -6.5 / Current Spread: 49ers -7

Opening Total: 40.5 Points / Current Total: 39.5 Points

The 49ers have won seven games in a row and are on a 5-0 ATS run.

NFL Week 16 Picks

Philadelphia Eagles vs. Dallas Cowboys

Opening Spread: Cowboys -1 / Current Spread: Cowboys -1.5

Opening Total: 51 Points / Current Total: 51 Points

The Eagles are 2-5 ATS on the road. This NFC East battle is a must-watch game this weekend.

Las Vegas Raiders vs. Pittsburgh Steelers

Opening Spread: Steelers -1 / Current Spread: Steelers -2.5

Opening Total: 40.5 Points / Current Total: 40.5 Points

The Raiders are 3-1 as an underdog this season. Pittsburgh are just 2-3-1 ATS at home.

Green Bay Packers vs. Miami Dolphins

Opening Spread: Dolphins -4.5 / Current Spread: Dolphins -4.5

Opening Total: 46.5 Points / Current Total: 46.5 Points

Miami have lost three in a row, but are 5-1 (4-2 ATS) at home this season.

Denver Broncos vs. Los Angeles Rams

Opening Spread: Broncos -1 / Current Spread: Broncos -1

Opening Total: 35.5 Points / Current Total: 35.5 Points

Denver are 1-6 (3-4 ATS) on the road this season. The Rams are on a 2-0 ATS run.

Tampa Bay Buccaneers vs. Arizona Cardinals

Opening Spread: Buccaneers -3 / Current Spread: Buccaneers -4.5

Opening Total: 41 Points / Current Total: 41.5 Points

Tampa have lost two in a row and are on a 0-4 ATS run. Arizona have lost four games in a row.

Los Angeles Chargers vs. Indianapolis Colts

Opening Spread: Chargers -3.5 / Current Spread: Chargers -3.5

Opening Total: 46.5 Points / Current Total: 47 Points

The Chargers are 5-2 ATS on the road. The Colts are on a 0-4 (2-2 ATS) run.