NFL Week 1 Opening Lines and Odds Comparison

We’re going to analyze NFL week 1 opening lines and see how much line movement there has been based on the betting action. We’ll be releasing this article every week throughout the season.

NFL Betting Sites

We’ll also have a weekly betting recap in these articles, but since it’s week 1, there’s nothing to recap.

Analyzing NFL Week 1 Line Movement

Let’s get right into comparing NFL week 1 opening lines to the current odds widely available.

Buffalo Bills vs. Los Angeles Rams

Opening Spread: Bills -1 / Current Spread: Bills -2.5

Opening Total: 52 Points / Current Total: 52.5 Points

Now is the best time to bet the Bills to cover ATS, as this line could hit -3 or more before kick-off.

New Orleans Saints vs. Atlanta Falcons

Opening Spread: Saints -3.5 / Current Spread: Saints -5.5

Opening Total: 42 Points / Current Total: 42.5 Points

The Saints are getting most of the action, but if this trends higher, the Falcons are a live underdog.

San Francisco 49ers vs. Chicago Bears

Opening Spread: 49ers -6.5 / Current Spread: 49ers -7

Opening Total: 42 Points / Current Total: 41.5 Points

Trey Lance is getting the start and there may be some growing pains early in the season for the 49ers.

Pittsburgh Steelers vs. Cincinnati Bengals

Opening Spread: Bengals -6 / Current Spread: Bengals -6.5

Opening Total: 44 Points / Current Total: 44.5 Points

As long as the spread stays below a TD, it’s tough to look past the Bengals in week 1 at home.

Philadelphia Eagles vs. Detroit Lions

Opening Spread: Eagles -3.5 / Current Spread: Eagles -4

Opening Total: 46.5 Points / Current Total: 48.5 Points

The total has jumped two points already in what should be a shootout in Detroit.

NFL Week 1 Odds

New England Patriots vs. Miami Dolphins

Opening Spread: Dolphins -2.5 / Current Spread: Dolphins -3

Opening Total: 44.5 Points / Current Total: 46.5 Points

It’s never a good feeling betting against Belichick, but the Dolphins should be explosive in 2022.

Baltimore Ravens vs. New York Jets

Opening Spread: Ravens -4.5 / Current Spread: Ravens -7

Opening Total: 45 Points / Current Total: 44.5 Points

The Ravens have seen a big increase in the spread and we’ve seen -7.5 at several shops already.

Jacksonville Jaguars vs. Washington Commanders

Opening Spread: Commanders -3.5 / Current Spread: Commanders -3

Opening Total: 44.5 Points / Current Total: 43.5 Points

Will the Jags show improvement with Doug Pederson? The Jags are getting 67% of the action so far.

Cleveland Browns vs. Carolina Panthers

Opening Spread: Browns -3.5 / Current Spread: Panthers -2.5

Opening Total: 42.5 Points / Current Total: 41.5 Points

With Deshaun Watson suspended, the spread has moved in favor of the Panthers for NFL week 1.

Indianapolis Colts vs. Houston Texans

Opening Spread: Colts -7.5 / Current Spread: Colts -8.5

Opening Total: 44.5 Points / Current Total: 46 Points

The Texans will likely be a mess in 2022, but can the Colts cover the biggest spread of the week?

NFL Week 1 Picks

New York Giants vs. Tennessee Titans

Opening Spread: Titans -6.5 / Current Spread: Titans -5.5

Opening Total: 44.5 Points / Current Total: 43.5 Points

Action has been relatively split on the spread and we’ve seen it drop a full point already.

Green Bay Packers vs. Minnesota Vikings

Opening Spread: Packers -1.5 / Current Spread: Packers -1.5

Opening Total: 48.5 Points / Current Total: 48 Points

There has been barely any line movement between this heated rivalry match-up.

Kansas City Chiefs vs. Arizona Cardinals

Opening Spread: Chiefs -2.5 / Current Spread: Chiefs -4.5

Opening Total: 53 Points / Current Total: 53.5 Points

The biggest total for NFL week 1 has jumped a ½ point and could continue moving up this week.

Las Vegas Raiders vs. Los Angeles Chargers

Opening Spread: Chargers -4 / Current Spread: Chargers -3.5

Opening Total: Raiders 51.5 Points / Current Total: 52 Points

The Raiders are getting slightly more action early on and this line could drop to a FG before kick-off.

Tampa Bay Buccaneers vs. Dallas Cowboys

Opening Spread: Buccaneers -2 / Current Spread: Buccaneers -1.5

Opening Total: 51.5 Points / Current Total: 50 Points

Handicappers are expecting some defense in this game, as the total has dropped 1.5 points already.

Denver Broncos vs. Seattle Seahawks

Opening Spread: Broncos -4 / Current Spread: Broncos -6

Opening Total: 41.5 Points / Current Total: 43 Points

How bad will the Seahawks be? Bettors are backing Russell Wilson to defeat his old team.