The Eastern New Mexico Greyhounds are the athletic team that represent Eastern New Mexico University, located in Portales, New Mexico, in NCAA Division II intercollegiate sports.

The Greyhounds compete as members of the Lone Star Conference for all 12 varsity sports. Until 2015, Eastern New Mexico had used Zias for the names of female sports teams, but the school announced that Eastern New Mexico will end the use of the Zias name for the female teams, choosing to the have Greyhounds for both male and female teams.