Salve Regina University competes on the NCAA Division III level and is a member of the Commonwealth Coast Conference (CCC) and New England Football Conference (NEFC). The university offers 10 varsity sports for women (soccer, field hockey, tennis, cross country, basketball, ice hockey, volleyball, softball, track and field, and lacrosse), eight for men (football, cross country, soccer, basketball, ice hockey, tennis, baseball, and lacrosse), and one co-ed sport (sailing).

Sailing is governed by the Intercollegiate Sailing Association (ICSA), and its subdivision, the New England Intercollegiate Sailing Association. The school also offers men`s and women`s rugby, governed by the Colonial Coast