We have reached the final week of the 2025-26 NFL regular season. And, surprisingly, we not only have three division crowns up for grabs but we also have the no.1 seeds in both conferences available for the taking. Week 18 is definitely shaping up to be a thrilling conclusion to an exciting season.

In Week 17, we expanded our parlay card to include five legs. Unfortunately, the Buccaneers and Rams played well below their standards and costs us wins. We were left with a 3-2 record for the week. This was a slight drop off from our 3-1 record in Week 16.

For the final week of the regular season, we’re looking at teams that are still playing with confidence, have momentum, and should win their matchups this weekend.

Our Week 18 parlay card starts with Bo Nix and the Denver Broncos as they host the Chargers. LA’s Justin Herbert isn’t playing, while Denver is aiming to capture the top seed in the AFC. The Jaguars at home, playing for the AFC South title is another lock for our NFL picks this weekend.

While those two are softballs, we’re looking at some inside fastballs with the Vikings hosting the Packers who will rest their starters for the Playoffs in two weeks. We also like the Cowboys to vanquish the Giants in a rivalry game. Dallas is still playing with effort, while the Giants should tank to lock in a Top 3 draft pick next year.

Speaking of next year, the Broncos and Jaguars are legitimate contenders to represent the AFC in the 2026 Super Bowl. There are no Underdogs this week as we are looking for a win as we reduce some risk  at the top sports betting sites.

With that said, NFL betting can be tricky at times. Fortunately, NFL parlays are one way to maximize betting value when the boards seem difficult to decipher. Let’s take a closer look at the best NFL parlays for Week 18.

NFL Picks and Parlays

Team	Odds	Payout Per Leg
Denver Broncos	-800	$12.50
Minnesota Vikings	-290	$51.29
Jacksonville Jaguars	-700	$72.90
Dallas Cowboys	-250	$142.06

This week, we’re taking four NFL teams that are all favored. Heading into Week 18, Favorites are 171-84-1, which is a 67.1% winning percentage. Favorites went 9-7 SU in Week 17.

Four of our Week 18 parlay picks are home teams. On the season, Home Favorites are 97-47 which is a 67.4% winning rate.

Of our Week 18 NFL parlay picks, only the Dallas Cowboys are an Away Favorite. For the season, Away Favorites are 74-37-1, which is a 66.1% winning rate. Away Favorites went 7-4 in Week 17.

 The Broncos and Jaguars are massive favorites with spreads sitting higher than 12 points. The Vikings are 6.5 favorites while the Cowboys are the smallest favorites of our parlay picks at just 3.5 points.

Over the last two months, we’ve gone 26-11 in our NFL parlay picks, which led to a winning ticket (4-0) in Week 11 and five 3-1 records for Weeks 9, 10, 12, 15, and 16. Weeks 13 and 14 were a 2-2 split. Week 17 saw a 3-2 finish on a larger parlay ticket. We’ve not had a losing record for parlay picks all season long.

With that said, make sure you continue to monitor the NFL odds throughout the week as they could shift as we get closer to kickoff, which will impact your total payout for this parlay card. For more NFL advice and picks, check out the best handicapping membership in the industry.

NFL Parlay Picks

The following is our best parlay NFL picks for Week 18:

NFL Parlay Pick 1: Denver Broncos (-1000) vs. Kansas City Chiefs

The Kansas City Chiefs were eliminated from the postseason two weeks ago when they also lost Patrick Mahomes to a torn ACL. Last week, they were crushed by the Tennessee Titans 26-9 when they also lost backup QB Gardner Minshew to a knee injury. KC will roll out a third-string QB Chris Oladokun to play against one of the league’s best defenses in the Denver Broncos.

This game is going to be an ugly one on Christmas night. There’s no scenario where the Chiefs can play spoiler considering that they are going with an inexperienced QB behind an inconsistent offensive line and a subpar running game.

Denver not only has one of the best defenses in the NFL, they also feature a pass rush that has the sNFL Parlay Pick #1: Los Angeles Chargers vs. Denver Broncos (-800)

The Los Angeles Chargers were involved in a must-win scenario last weekend in order to still compete for the AFC West crown and an outside shot at the top seed. Unfortunately, they ended up losing at home to the Houston Texans, which was our top upset pick of the week.

So, LA decided that seeding doesn’t matter for the Playoffs as they will finish with one of the three Wild Card spots and have already announced that QB Justin Herbert will sit out this weekend’s matchup.

Without Herbert, the Chargers have no chance at beating the Broncos in Denver this weekend. With a win, Denver will lock up the AFC’s top spot and a first round bye. So, you can imagine how inspired this team is going to play.

These two teams already played on September 21, and the Chargers won at home by the score of 23-20. You can throw that result out because Denver is going to win this game by double digits. I would also expect the Chargers to rest other starters, as well. There’s no need to risk injury, especially with the Playoffs coming the next week.

The Broncos are 10-2 SU in their last 2 games at home against the Chargers. Furthermore, they’re 9-1 SU at home this season and 12-1 SU in their last 13 games.

Denver’s defense will dominate the LA backups, while Bo Nix and company put up enough points to win by a comfortable margin.

NFL Parlay Pick #2: Green Bay Packers vs. Minnesota Vikings (-290)

Despite being eliminated from the Playoffs three weeks ago, the Minnesota Vikings (8-8) have won four games in a row. Two of those wins were against teams fighting for their playoff lives (Dallas, Detroit). In fact, those defeats at the hands of the Vikings eliminated both the Lions and Cowboys from making the Playoffs.

I expect Minnesota to extend their winning streak to a 5^th consecutive victory this weekend. Green Bay has suffered significant injuries all season long. With a postseason berth already clinched, I don’t see this team playing their starters in Week 18. It makes no sense to play the starters, especially considering that the fact that the Packers are locked into the no.7 seed and can’t move up even with a win.

This means the Vikings will be playing against backups for the most part. And, considering that Minnesota is looking to finish the season strong, and with a winning record, I really like the Vikings in this spot.

Minnesota is 4-1 SU and 4-1 ATS in their last five games. They’re 14-4 SU as the favorite, which they are this weekend at home.

Without Micah Parsons, this Green Bay defense is average at best. They’ve given up at least 400 total yards in each of their last two games and I don’t see that trend stopping this weekend.

Look for Minnesota to ride their running game, especially after the Baltimore Ravens just put up 307 rushing yards against the Packers last weekend.

From there, the play action game is going to be huge for the Vikings as their trio of Jefferson, Addison and Hockenson should feast on Sunday. Take the Vikings to win this game outright and finish the season on a strong note.

NFL Parlay Pick #3: Tennessee Titans vs. Jacksonville Jaguars (-700)

In their first meeting this season, the Jacksonville Jaguars (12-4) beat the Titans 25-3. That win bumped their record to 6-1 SU against Tennessee over the last 3.5 seasons. With what’s on the line for the Jags this weekend, I expect Jacksonville to win big on Sunday at home.

The Jaguars can secure the AFC South title with a win, and still have an outside shot at the top seed in the AFC. They’re 7-0 SU in their last seven games which includes a thrashing of the Broncos in Denver a few weeks ago.

The Jags have the NFL’s top run defense as they allow only 86.1 ypg. This unit will shut down any attempts by Tennessee to run the ball. They will also limit Cam Ward’s passing on Sunday and get after him with a Top 10 sack rate.

I also see Jacksonville forcing turnovers in this game as they rank 2^nd in the league at 1.9 takeaways per game. Tennessee gives the ball up 1.1 times per game. Additionally, the Titans have the third highest penalty rate at 7.8 per game.

While the Jags have a similar rate, Tennessee’s ineptness on offense combined with a rookie QB on the road, makes me confident in Jacksonville to win by two touchdowns or more this weekend.

The Jags are 3-0 SU as a home favorite, 9-2 SU in the AFC, and 4-1 SU in the division. The Titans are 0-5 SU in the AFC South this year and 2-5 SU in road games.

This matchup is set up perfectly for the Jaguars to make a big statement heading into the Playoffs.

NFL Parlay Pick #4: Dallas Cowboys (-250) vs. New York Giants

The Dallas Cowboys (7-8-1) snapped a three-game losing streak by defeating the Washington Commanders on the road last weekend. Ever since their big Thanksgiving win over the Kansas City Chiefs, Dallas dropped the ball literally and figuratively as they failed to make the postseason.

While many would point the finger at Jerry Jones and the Micah Parsons trade, the reality is that this team has one of the worst defenses in the league. Sure, adding to the defensive line with their trades this season was a good thing, but their backend is awful. Getting rid of Diggs doesn’t help either.

And, yet, I am still taking the Cowboys to close out the season with a win and prevent another losing season.

The New York Giants sit at 3-13 on the season and just beat the Raiders which gave Las Vegas the no.1 pick in the NFL Draft next year. Currently, the Giants have the no.2 overall draft pick. I can’t see this team blowing that high of a pick for no reason. A win this weekend could drop them to 6^th through 8^th. If that happens, then you must look at the Ownership as the cause for this dysfunction.

In their first meeting back in September, Dallas won 40-37. I don’t see this game being that high of a score but I wouldn’t be surprised if each team flirted with 30 points apiece.

Dallas’s no.1 passing attack (274.0 ypg) will face a subpar Giants pass defense (218.7 ypg) and I like the Cowboys in that matchup. I also like their no.9 rushing attack (124.6 ypg) to feast on New York’s run defense that gives up the second most rushing yards in the league (145.4 ypg).

While New York will do well against Dallas’ no.32 ranked pass defense (253.6 ypg), I just don’t see the Giants giving Dart or this offense the green light to go all out. Look for a spirited effort at times, but for Dallas to win in similar fashion to their victory last weekend against Washington.

Dallas is 9-0 SU in their last nine games versus the Giants. They’re also 7-1 SU in their last eight trips to New York (New Jersey). Furthermore, the Cowboys are 4-1 SU in the NFC East this season. The Giants are 2-5 SU at home this season and 1-10 SU in their 11 NFC games.

Take Dallas to win and cover!

NFL Parlay Total Payout

• Denver Broncos (-800)
• Minnesota Vikings (-290)
• Jacksonville Jaguars (-700)
• Dallas Cowboys (-250)

The Denver Broncos and Jacksonville Jaguars are the biggest favorites this weekend. Both teams are at home and playing against weaker opponents. The Jags will clinch the AFC South with a win this weekend, while Denver can clinch the AFC’s top seed.

Minnesota has been playing with swagger the last month and should win at home over Green Bay who will most likely rest its starters. Dallas on the road would normally be a concern, but the Cowboys are facing a New York Giants team that could lock up the no.2 draft pick with a loss.

If you take all four legs of this NFL parlay card, then you would score a $142.06 payout.

Remember, to wager on this parlay card, you will need to check out the best sports betting sites and take advantage of any optimal lines, which means some line shopping could be greatly beneficial.

If you are loving these NFL parlay picks, then check out our College Football parlays of the week and double down on this weekend’s gridiron action.