If you plan on doing any NFL betting in Week 12, chances are that you’ll be looking for some good NFL player props. I’m here to point you to some winning plays, with five Week 12 NFL player props bets in particular standing out.

The road to this year’s Super Bowl is getting clearer with each passing week, and our goal is to keep handing you winning NFL picks to cash in on. This week’s batch of NFL player props should be able to do that on average, but if you want even more help, stop by our Week 12 NFL predictions before finalizing your bets.

With that, let’s see what I’m cooking up for this week.

NFL Player Prop Odds

A week after nailing four of five NFL player props, we took a big step back. I did have some close calls, as DK Metcalf missed a push by one yard. However, my Week 11 NFL player prop bets ultimately missed the mark as a whole.

This week can’t get worse by default, but hopefully we can start the week off with a win on Thursday Night Football. There are a surprising amount of palatable props in the TNF game.

NFL player prop betting is fun because it is not necessarily contingent on what happens in a given game, while you have so many options in front of you. I’ve gathered up another five-pack of my favorite NFL player prop bets, so you can roll with the list above by reading on for a little more insight into each pick. Or, check out the industry’s top handicapping membership for more great NFL picks each week.

NFL Player Props Today

Here’s a breakdown of each prop, analyzing matchups, trends, and key factors to help you make informed NFL bets:

Josh Allen – Over 33.5 Rushing Yards (-114)

Matchup: Buffalo Bills @ Houston Texans

The Buffalo Bills offense goes as Josh Allen does, which usually means he has to take off running to move the ball at times. He certainly did damage on the ground last week (3 touchdowns!), and an elite Houston Texans pass rush will probably force him out of the pocket more than a few times on Thursday Night Football.

Houston has admittedly done a good job against mobile quarterbacks, but in terms of rushing yardage allowed to the position, they’re more middle of the pack. Necessity and offensive style work together to likely allow Allen to threaten a rushing yardage total that ultimately feels a bit low.

Allen topped 33.5 rushing yards last week and has done so five times on the year. He’s come awfully close two other times with 31 and 30 rushing yards, too.

The matchup isn’t perfect, but with Houston’s stiff run defense likely neutralizing James Cook and the pass rush flushing the mobile Allen out, I can see him crushing this prop bet.

Rashee Rice – Over 70+ Receiving Yards

Matchup: Indianapolis Colts @ Kansas City Chiefs

Another week 12 NFL player prop bet that feels like a lock is this Rashee Rice receiving yardage total. Since returning from injury and suspension, Rice has been the focal point of Kansas City’s passing game, registering 7+ targets in all four of his games.

Rice has turned that huge role into 7+ catches twice and last week he had six catches, while he’s topped this specific yardage total twice already.

In week 12 Rice will be at home against the Colts, who have been quite beatable through the air on the season. So far, they are giving up the 11th most receiving yards to wide receivers and when you factor in Rice’s role and talent, it’s an easy call.

In a game with a nice 49.5 total – and one the 5-5 Chiefs have to have – look for Rice to be heavily involved and productive enough to hit the Over.

Drake Maye – Over 1.5 Passing TDs (-178)

Matchup: New England Patriots @ Cincinnati Bengals

The price isn’t to die for with this prop, but it’s a great stand alone bet, or one you can tack on any of your NFL parlays in week 12.

Maye has been an NFL MVP candidate for much of the year, while he enters the week with 20 passing scores to his name. Just as important, Maye has found a way to throw at least one touchdown pass in all but one game in 2025, and he’s had two or more in eight different contests.

This week’s game – a date with a poor Cincinnati Bengals defense – is as good of a time as anyone to smash a Drake Maye touchdown prop. The Bengals just gave up 34 points to the Pittsburgh Steelers last week and have allowed 27+ points in nine consecutive games.

Cincy has been bad across the board, but they have definitely struggled against the pass. In addition to giving up the 5th most passing yards on the year, they’ve gotten burned for the 3rd most passing touchdowns as well.

Most Patriots player props will look appealing in this spot, but Maye to toss two scores takes the cake for me.

Derrick Henry – Over 85.5 Rushing Yards (-114)

Matchup: New York Jets @ Baltimore Ravens

Another great week 12 NFL player prop is Derrick Henry’s rushing yardage. He is coming off a fantastic 102-yard outing against the Cleveland Browns, and the matchup he has in front of him this week isn’t nearly as difficult.

Last week’s 100-yard performance came against one of the best run defenses in the entire league, but Henry gets at best a middling New York Jets front seven. New York also traded away top run stuffer Quinnen Williams not too long ago, while the recent benching of quarterback Justin Fields has Gang Green coming in as massive 13.5-point underdogs.

Everything points to a big win for the Baltimore Ravens, who also have major incentive to pile up victories as they try to bounce back from a slow start in the AFC North. With their division technically not out of reach and a win in their sights, look for Henry to get fed the rock early and often.

Henry has had his rough spots in 2025, but he looked good last week (5.7 yards per carry) and has topped this exact rushing yardage total in three of his last five games.

Jacoby Brissett – Over 1.5 Passing TDs (-118)

Matchup: Jacksonville Jaguars @ Arizona Cardinals

Okay, let’s try this one again. One of my favorite NFL player props last week was for Justin Herbert to exploit a weak Jacksonville Jaguars defense for 2+ passing scores. Unfortunately, the cross-country travel and not having his top offensive tackle was too much for him to overcome.

This week it will be the Jags who have to travel across the country. Arizona gets to play at home, too, while the matchup is still ripe for the plucking. Jacoby Brissett is far from a household name, but he’s actually been ablaze, topping this prop in each of his last five games.

That’s right, Brissett has thrown multiple touchdown passes in all of those starts and in week 12 he faces a Jacksonville defense that is tied for the 3rd most touchdown passes allowed on the season.

Whether he feasts early or is playing catch-up late, I tend to think Brissett will keep producing in what looks like a smash spot.

The Best Week 12 NFL Player Props Parlay

• Josh Allen – Over 33.5 Rushing Yards (-114)
• Rashee Rice – Over 70+ Receiving Yards (-152)
• Drake Maye – Over 1.5 Passing TDs (-178)
• Derrick Henry – Over 85.5 Rushing Yards (-114)
• Jacoby Brissett – Over 1.5 Passing TDs (-118)

Be sure to look around for the best possible NFL odds for whatever week 12 NFL player props you decide to target. That’s even more so the case if you want to toss my favorite prop bets into your NFL parlays, as you’ll certainly want maximum upside if you’re taking on maximum risk.

I prefer to target NFL player prop bets individually as straight bets, but I like all of these and am confident they can hit. Barring injury or something crazy, they have a terrific chance of doing that in week 12, but if you want just one bet that stands above the rest, I think it’s Henry to top 85.5 rushing yards. Talent, role, matchup, odds, and game script are all likely to combine to give him the best shot of hitting this week.

You have my favorite NFL player props and my reasoning for each pick. If you choose to add these five player props to an NFL parlay card, then you would win $1,586 for every $100 wagered.

For the NCAAF fans out there, you can also roll with our best College Football parlays of the week for more exciting football betting action.