Best NFL Week 6 Predictions

We have uncovered the best NFL Week 6 predictions. After analyzing the point spread and game total betting markets, we have identified the top three ATS picks and top three over/under picks.

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Last week, I ended up going 3-3. My three point spread picks lost, but I went 3-0 on game totals. I’ll look to turn a profit with my NFL Week 6 predictions. The Packers and Steelers are on a bye week.

NFL Week 6 Predictions – Against the Spread

Here are the top three NFL Week 6 predictions covering the point spread market:

Best Bet: San Francisco 49ers -9 (-110)

The Browns (2-2 / 2-2 ATS) host the 49ers (5-0 / 4-1 ATS) on Sunday. PJ Walker will start at QB for the Browns, as Deshaun Watson remains out. Brock Purdy leads the NFL in QB rating (123.1). I can’t see how the Browns are going to score more than ten points in this game with Walker at QB.

NFL ATS Odds

Best Bet: Philadelphia Eagles -6 (-110)

The Jets (2-3 / 3-2 ATS) are coming off a win against the Broncos. The Eagles (5-0 / 3-1-1 ATS) are one of two undefeated teams left. The Eagles are scoring 28.2 PPG (5th). Philadelphia’s offense averages 164.0 RYPG (2nd) and the Jets allow 146.2 RYPG (29th). Philly should run all over this defense.

Best Bet: Los Angeles Rams -7 (-110)

The Rams (2-3 / 3-1-1 ATS) host the Cardinals (1-4 / 3-2 ATS) on Sunday. The Rams got Cooper Kupp back last week and he performed great. They have lots of depth at WR. The Rams offense is averaging 270.0 PYPG (5th) and the Cardinals allow 251.4 PYPG (26th). I like the Rams to win by double-digits.

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NFL Week 6 Predictions – Game Totals

Here are the top three NFL Week 6 predictions covering the game totals market:

Best Bet: Panthers vs. Dolphins Over 47.5 Points (-110)

The Dolphins (4-1) have gone over in three of five games. They’re the highest-scoring team in the NFL (36.2 PPG). The Panthers (0-5) are allowing 28.8 PPG (28th). The Lions scored 42 points against the Panthers last week. Miami have allowed 16+ points in every game. This game will have 50+ points.

NFL ATS Picks

Best Bet: Lions vs. Buccaneers Over 42 Points (-110)

The Lions (4-1) lead the NFC North and are scoring 29.6 PPG (4th). The Buccaneers (3-1) lead the NFC South. Tampa Bay are scoring 21.0 PPG (T20) and only allowing 17.0 PPG (8th). However, the Lions are playing great on offense and if they score 27+ points, this game will go over the total with ease.

Best Bet: Giants vs. Bills Over 43.5 Points (-110)

The Bills (3-2) are scoring 31.8 PPG (3rd) and the Giants (1-4) allow 30.6 PPG (29th). Buffalo are coming off a loss in London and will want to bounce back quickly at home. Buffalo could score 40+ points against this defense. The Giants won’t need to score many points for this game to go over the total.