Best NFL Thanksgiving Day Picks

We have the best NFL Thanksgiving Day picks for all three games tomorrow. The action kicks off with the Lions hosting the Packers. The Commanders play the Cowboys and the 49ers play the Seahawks.

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The games can be watched live on FOX, CBS and NBC.

All three matchups are divisional games featuring NFC teams. All three games feature bitter rivals. We’re sure to have some exciting football tomorrow. Let’s uncover the best NFL Thanksgiving Day picks.

Packers vs. Lions Picks for Thanksgiving Day

Kick Off: 12:30 PM ET

Point Spread: Packers +7.5 (-110) vs. Lions -7.5 (-110)

Game Total: Over 47.5 Points (-110) vs. Under 47.5 Points (-110)

The Packers (4-6 / 5-5 ATS) are 1-4 (2-3 ATS) on the road. The Lions (8-2 / 7-3 ATS) are 4-1 (3-2 ATS) at home. The Lions have won the last four consecutive games against the Packers (4-0 ATS).

Green Bay have been strong against the pass, as they allow 193.2 PYPG (7th). GB allow 134.7 RYPG (28th) and the Lions offense averages 136.6 RYPG (5th). David Montgomery and Jahmyr Gibbs are in position to have big games. Detroit have lost six Thanksgiving Day games in a row.

I predict the Lions will break that streak, but the Packers will cover ATS in a close game.

Best Bet: Green Bay Packers +7.5 (-110)

NFL Thanksgiving Day Odds

Commanders vs. Cowboys Picks for Thanksgiving Day

Kick Off: 4:30 PM ET

Point Spread: Commanders +12.5 (-110) vs. Cowboys -12.5 (-110)

Game Total: Over 49 Points (-110) vs. Under 49 Points (-110)

The Cowboys (7-3 / 7-3) have been perfect at home this season (4-0 / 4-0 ATS). The Commanders (4-7 / 5-5-1 ATS) are 5-1 ATS on the road. Since 2021, the Cowboys are 3-1 (3-1 ATS) against Washington.

Dallas are scoring 30.2 PPG (2nd) and allowing 17.5 PPG (5th). The offense is averaging 255.5 PYPG (5th). The Commanders are allowing 258.5 PYPG (30th). Dallas have scored 33+ points in three of their last four games. Washington have scored 19+ points in four consecutive games.

One of my best NFL Thanksgiving Day picks is on the over 49 points in this game.

Best Bet: Over 49 Points (-110)

NFL Thanksgiving Day Picks

49ers vs. Seahawks Picks for Thanksgiving Day

Kick Off: 8:20 PM ET

Point Spread: 49ers -7 (-110) vs. Seahawks +7 (-110)

Game Total: Over 44 Points (-110) vs. Under 44 Points (-110)

The 49ers (7-3 / 5-5 ATS) have beat up on the Jaguars and Buccaneers the last two weeks after losing three consecutive games before their bye week. The Seahawks (6-4 / 4-5-1 ATS) are 4-1 (1-3-1 ATS) at home this season. Last season, the 49ers went 3-0 (3-0 ATS) against Seattle, including the playoffs.

Seattle averaged just 14.3 PPG against San Francisco last season. The 49ers are scoring 27.9 PPG (3rd) and allowing 15.7 PPG (1st) this season. Brock Purdy has 18 passing TDs and just five INTs.

I expect the 49ers to dominate the Seahawks despite being on the road.

Best Bet: San Francisco 49ers -7 (-110)

Expert NFL Thanksgiving Day Picks

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