NFL Week 18 Point Spread Predictions

It’s the final week of the NFL regular season, but there’s still lots to play for. The wild card races in the AFC and NFC are still ongoing, so you can guarantee this will be an exciting weekend.

NFL Sportsbooks

All teams are in action, with two games on Saturday and 14 games on Sunday.

Here are the top five ATS picks for week 18:

Browns vs. Steelers Week 18 ATS Pick

Best Bet: Steelers -2.5 (-115)

The Pittsburgh Steelers (8-8 / 9-6-1 ATS) host the Cleveland Browns (7-9 / 8-8 ATS). The Steelers are on a 3-0 (3-0 ATS) run and can still earn the second wild card spot in the AFC.

To make the playoffs, Pittsburgh needs to win, while the Dolphins and Patriots need to lose.

The Browns won the first H2H meeting at home in week 3 (29-17). The home team is 7-3 ATS in the last ten H2H games and the Steelers are 4-1 ATS in the last four meetings in Pittsburgh.

NFL Point Spread Odds

Panthers vs. Saints Week 18 ATS Pick

Best Bet: Panthers +4.5 (-110)

The Carolina Panthers (6-10 / 8-8 ATS) take on the New Orleans Saints (7-9 / 7-9 ATS) to finish up the regular season. Both teams have already been eliminated from the playoffs.

Carolina are 8-4 ATS as an underdog this season. The Panthers are also 7-3 ATS in the last ten H2H games against the Saints and 4-1 ATS in the last five H2H games played in New Orleans.

Rams vs. Seahawks Week 18 ATS Pick

Best Bet: Seahawks -6.5

The Seattle Seahawks (8-8 / 7-9 ATS) host the Los Angeles Rams (5-11 / 5-10-1 ATS). This line opened at -4.5 in favor of the Seahawks and I recommend jumping on the -6.5 line while it’s available.

The Rams are just 1-5-1 ATS on the road this season and 3-6-1 as an underdog. Seattle can make the playoffs with a win and a Lions win or tie. The home team is 5-2 ATS in the last seven H2H meetings.

NFL Point Spread Picks

Patriots vs. Bills Week 18 ATS Pick

Best Bet: Patriots +7.5 (-110)

The New England Patriots (8-8 / 7-8-1 ATS) need to defeat the Buffalo Bills (12-3 / 7-7-1 ATS) to ensure a spot in the playoffs. The Bills are just 3-4 ATS at home this season, but they’ve won six games in a row.

Buffalo are also 4-1 ATS in the last five H2H games, but with so much on the line for the Patriots and the Bills already safely in the playoffs, look for the Patriots to keep this game within a touchdown.

Texans vs. Colts Week 18 ATS Pick

Best Bet: Texans +3 (-110)

The Indianapolis Colts (4-11-1 ATS / 6-10 ATS) host the Houston Texans (2-13-1 / 7-8-1 ATS) to close out the season for both teams. The road team is 12-4-2 ATS in the last 18 H2H meetings.

The Colts are just 1-5 ATS at home this season, while the Texans are 4-3-1 ATS on the road. The Colts are on a six-game losing streak and the Texans will find a way to win a low-scoring affair.

Read our point spread betting guide next if you’re new to online gambling.