San Francisco 49ers vs Seattle Seahawks Picks and Predictions November 17th 2024

The 49ers are heavily favored at -293 on the money line as they host the Seahawks at 4:05 ET on Sunday, November 17th at Levi’s Stadium in Santa Clara, CA. The 49ers are -6.5 point favorites on the point spread. This week 11 NFC West matchup is being televised on FOX, with the over/under line set at 49.5 points.

Seattle vs. San Francisco Key Information

• Teams: Seahawks at 49ers
• Where: Levi’s Stadium Santa Clara
• Date: Sunday, November 17th
• Betting Odds SF -293 | SEA +239 O/U 49.5

The Seahawks Can Win If…

Seattle heads into week 11 against the 49ers looking to snap a two-game losing streak, which includes a 31-10 loss to the Bills in week 8 and a 26-20 loss to the Rams in week 9. The Seahawks are now 4-5, putting them 4th in the NFC West. They have a 2-1 record on the road but are just 2-4 at home.

According to our power rankings, Seattle is 22nd in the NFL and has a 6.3% chance of making the playoffs and a 3.7% chance of winning the division. Their average scoring margin this season is -1.2 points per game, and they are 2-6-1 against the spread. Their O/U record is 5-4, with the under hitting in three straight games.

Heading into week 11, the Seahawks rank 20th in our offensive power rankings. They lead the NFL in passing yards per game with 268.2, while ranking 2nd in passing attempts. Geno Smith threw for 363 yards in week 9, with 3 touchdowns and 3 interceptions, after posting a passer rating of 78 in week 8 and 110 in week 7. Jaxon Smith-Njigba had a big performance in week 9, catching 7 passes for 180 yards and 2 touchdowns.

Seattle is 27th in rushing yards per game, averaging 91.2 yards on 22.3 attempts per game. Kenneth Walker III rushed for 83 yards on 25 carries in week 9. The Seahawks have struggled on 3rd down, converting just 35.2% of their attempts, which ranks 23rd in the NFL.

In their 26-20 overtime loss to the Rams, the Seahawks’ defense gave up 298 passing yards and 68 rushing yards on 24 attempts. They allowed two passing touchdowns and struggled to generate pressure, finishing with no sacks and losing the QB hit and tackles for loss differentials.

The defense did force one interception and held the Rams to just a 23.1% conversion rate on third downs. Overall, the Seahawks gave up 366 total yards and allowed the Rams to complete 56.8% of their passes.

• The Seahawks have gone 1-2 over their last three regular season games. Their record against the spread in this stretch is 1-2 to go along with an over-under mark of 0-3.
• Across Seattle’s last ten regular season games, their record sits at 5-5. In these contests, the team went just 2-7-1 against the spread, while going 5-5 on the over-under.

The 49ers Can Win If…

After a week 7 loss to the Chiefs, the 49ers have bounced back with two straight wins, including a 30-24 victory over the Cowboys in week 8 and a 23-20 win over the Buccaneers in week 10. San Francisco was favored by 6.5 points against Tampa Bay but couldn’t cover the spread, bringing their ATS record to 4-5. The 49ers have been favored in all of their games this season.

Heading into week 11, San Francisco has a 5-4 record, putting them 2nd in the NFC West. Our power rankings have the 49ers 6th, and they have a 49.6% chance of making the playoffs and a 35.7% chance of winning the division. Their O/U record is 5-4, with their games averaging 48.3 points per game.

Heading into week 11, the 49ers are 6th in our offensive power rankings. They are 2nd in the NFL in passing yards per game with 262.8, despite ranking 19th in passing attempts. They also rank 5th in rushing yards per game, averaging 149.7 on 30 attempts per game. San Francisco is 7th in 3rd-down conversions, with a 43.5% success rate, and they rank 3rd in red zone attempts, although their conversion rate of 21.1% ranks 22nd in the league.

Brock Purdy threw for 353 yards and 2 touchdowns on 25/36 passing in week 10, posting a passer rating of 119. Jauan Jennings led the team with 7 catches for 93 yards, while Christian McCaffrey had 39 rushing yards on 13 carries. The 49ers scored 10 points in the 4th quarter against the Buccaneers, after scoring 21 points in the 3rd quarter in week 8 against the Cowboys.

In their 23-20 win over the Buccaneers, the 49ers’ defense allowed just 105 passing yards. They limited Tampa Bay to 215 total yards and 110 rushing yards on 27 attempts. The 49ers’ defense also recorded two sacks and held the Buccaneers to a 35.7% conversion rate on third down.

Despite this, the Buccaneers did manage to find the endzone through the air, resulting in a 3.6% passing yards per attempt figure for the 49ers.

• The 49ers have gone 1-2 over their last three regular season games. In these matchups, they ended with an ATS record of 1-2 and an over-under mark of 1-2.
• Through their last ten regular season contests, San Francisco has a record of 6-4. In these matchups, they ended with an ATS record of 3-7 and an over-under mark of 6-4.

The Lean

Our pick against the spread is to take the Seahawks to cover as road underdogs in this week 11 matchup vs. the 49ers. Right now, the point spread lines have the 49ers at -6.5, and with our projected final score being 25-24 in favor of Seattle, this is a great spot to take the Seahawks to cover.

For an over/under pick, we are leaning towards the under, with a projected combined score of 49 points. The current O/U line is 49.5 points, making the under a good value play in this one.

49ers Reintroduce Christian McCaffrey to San Francisco, Rival Seahawks

The San Francisco 49ers (5-4), invigorated by the return of Christian McCaffrey, will look to extend their winning streak as they host the struggling Seattle Seahawks (4-5) on Sunday in Santa Clara, Calif. The 49ers, coming off back-to-back victories for the first time this season, have regained confidence with their Offensive Player of the Year back on the field.

McCaffrey’s Long-Awaited Return

After missing the first eight games of the season due to Achilles tendinitis, Christian McCaffrey returned to action in San Francisco’s 23-20 victory over Tampa Bay last week. Although limited compared to his usual game-breaking standards, McCaffrey still managed to impact the game with 39 rushing yards on 13 carries and six catches for 68 yards.

“I’m just happy I’m here,” McCaffrey said. “That was a long journey and a lot of long days, so it feels good to win and to just play in a football game again.”

Quarterback Brock Purdy, who threw for 353 yards and two touchdowns in the win, expressed his excitement to have McCaffrey back in the lineup, highlighting the running back’s ability to turn short passes into big plays.

Despite being listed as limited in practice this week, 49ers coach Kyle Shanahan downplayed concerns about McCaffrey’s workload. Shanahan noted that regular maintenance days will be part of the running back’s routine as he reacclimates to weekly action.

49ers’ Injury Updates

San Francisco’s offense and defense are dealing with several key injuries:

• George Kittle (hamstring): Missed practice time but is expected to play. Kittle had two touchdowns in the 49ers’ Week 6 win over Seattle.
• Nick Bosa (hip): Limited in practice but expected to suit up.
• Mitch Wishnowsky (back): The punter aggravated a prior injury, and his status remains uncertain.

Seahawks Looking to Recover

The Seahawks are struggling after a strong 3-0 start, losing five of their last six games, including a 36-24 defeat to the 49ers in Week 6. In that game, San Francisco’s ground game gashed Seattle’s defense for a season-high 228 rushing yards, even without McCaffrey on the field.

Seattle’s run defense continues to be a major issue, ranking 27th in the NFL, allowing 139.4 rushing yards per game. Despite their defensive woes, the Seahawks made a surprising move this week, releasing starting linebacker Tyrel Dodson, their leading tackler with 71 stops this season.

Seahawks coach Mike Macdonald, in his first year with the team, acknowledged the team’s struggles and emphasized the need for improvement:

“We’ve got guys that fought, but we have to go to work and make this right. We’re going to find the solution at some point.”

Key Players and Matchups

• Christian McCaffrey vs. Seattle’s Defense: McCaffrey’s return adds another layer to an already dominant 49ers rushing attack, and he has historically performed well against Seattle, averaging 129.5 rushing yards in two games against them last year.
• DK Metcalf: Returning from a two-game absence, Metcalf’s presence will be critical for a Seattle offense looking to stay competitive.
• Brock Purdy vs. Seattle’s Secondary: Purdy is coming off one of his best performances of the season and will aim to exploit Seattle’s defensive lapses.
• Seattle’s Offensive Line: With right tackle Abe Lucas possibly making his season debut, the Seahawks hope to stabilize their protection and open lanes for their running game.

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Outlook

The 49ers appear poised to capitalize on McCaffrey’s return and their home-field advantage as they seek to extend their winning streak. Meanwhile, the Seahawks face the daunting task of stopping a versatile San Francisco offense and shoring up a porous run defense.

Prediction: The 49ers’ balanced attack and reinvigorated roster will prove too much for Seattle, leading to a decisive win in Santa Clara.