Merry Christmas you “filthy animals”! That’s right, Week 17 features three games on Thursday, December 25. In fact, two of these three Christmas Day matchups appear to be presents for all of us good little boys and girls as they will have Playoff implications.

All three Christmas games featured divisional rivalries, which adds drama to an already intense week of action. The Dallas Cowboys head to Washington, the Detroit Lions are in Minnesota, and the Thursday Night game features the Denver Broncos at Kansas City Chiefs.

However, that’s not all! The Sunday slate features some thrilling matchups as well. None bigger than the main event of the week – Philadelphia Eagles at Buffalo Bills. This could be a Super Bowl preview.

On Sunday’s undercard are a handful of games that have Playoff implications on the line like the Texans vs. Chargers, Ravens vs. Packers, Bears vs. 49ers and Seahawks vs. Panthers.

With that said, let’s take a look at the NFL Week 17 odds and make our early Week 17 picks. There’s no shame in placing your Week 17 NFL bets ahead of time, as we do see some value on the boards.

NFL Week 17 Schedule

NFL Week 17 Odds

Week 17 is where the betting board starts to split between teams still pushing for playoff positioning and others already looking toward the offseason. That contrast creates some of the most actionable NFL odds of the season, especially when motivation and matchup advantages are clearly defined.

One of the marquee games of the week is Philadelphia Eagles vs. Buffalo Bills, a matchup featuring two physical defenses and quarterbacks who can flip a game late. This contest also profiles as one of the strongest spots on the slate for player prop bets, given the condensed usage among star skill-position players on both sides.

The Cincinnati Bengals vs. Arizona Cardinals game carries one of the higher totals on the board, with Cincinnati’s passing attack continuing to dictate tempo and Arizona struggling to generate consistent defensive stops. Totals like this tend to draw attention across the major sports betting sites, especially when compared to several slower-paced divisional games.

On the opposite end of the spectrum, Pittsburgh Steelers vs. Cleveland Browns sets up as one of the lowest totals of the week. Both teams lean heavily on defense and ball control, making this matchup a prime candidate for bettors targeting unders or situational sides. Games with profiles like this often end up on weekly Underdogs of the week lists.

There are also several heavy favorites worth monitoring, including Denver Broncos vs. Kansas City Chiefs and Detroit Lions vs. Minnesota Vikings, where large spreads test whether the favorite can maintain focus late in the season. These games often shape parlay construction and survivor strategy.

With that said, if you need any additional betting assistance for Week 17, or any other week of the 2025-26 NFL season, then check out the industry’s top handicapping membership and get access to thousands of NFL picks via elite handicappers. You can also take advantage of the free trial and celebrate Christmas in style with some football winnings.

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NFL Week 17 Predictions

Let’s take a look at the full slate of NFL Week 17 matchups and make our NFL picks for each game.

Dallas Cowboys vs. Washington Commanders Odds

The Dallas Cowboys enter Christmas with clear offensive advantages across the board, especially in the trenches. Washington’s defensive front has struggled to hold up against physical run games, and that problem was evident again last week as Philadelphia controlled pace and time of possession. Dallas is at its best when it can stay on schedule offensively, and this matchup sets up well for sustained drives rather than a pass-heavy script.

The Washington Commanders‘ quarterback situation adds further instability. Marcus Mariota was limited last week and ultimately ceded snaps, while Josh Johnson was forced into action behind an offensive line that allowed consistent pressure. Even if Mariota is able to start, mobility and arm strength remain questions on a short week. That uncertainty makes it difficult for Washington to threaten Dallas vertically or punish aggressive defensive looks.

The Commanders’ offense also lacks efficiency in early downs, which compounds issues against a Dallas defense that thrives when playing from ahead. Philadelphia exposed Washington’s inability to recover once game script turns negative, and Dallas is even more capable of forcing that scenario with a balanced rushing attack and efficient red-zone execution.

From a totals perspective, the number reflects Dallas’ scoring ceiling more than Washington’s. The Cowboys can generate points quickly if Washington’s defense breaks, but the Commanders’ offensive limitations cap shootout potential. Unless turnovers create short fields, Washington is unlikely to contribute consistently enough to push this game well past the mid-40s.

Dallas Cowboys vs. Washington Commanders Predictions

Spread: Cowboys -7
Dallas’ physical edge and Washington’s quarterback uncertainty create separation over four quarters.

Total: Under 50.5
Dallas can score, but Washington’s offensive floor keeps this from becoming a full shootout.

Moneyline: Cowboys -375
Dallas is the more complete team and controls matchup leverage throughout.

Bet: Cowboys -7, Under 50.5, Cowboys ML

Detroit Lions vs. Minnesota Vikings Odds

The Detroit Lions head to Minneapolis on short rest for the second game of the Christmas slate, facing a Minnesota Vikings team forced to adjust offensively with rookie Max Brosmer starting in place of the injured J.J. McCarthy. This quarterback change significantly alters Minnesota’s offensive ceiling and shifts the game toward a more conservative, possession-based approach. Against a Lions team still fighting for playoff positioning, the Vikings’ margin for error is extremely thin.

Detroit enters this matchup with clear motivation after a frustrating home loss, and the Lions’ offensive profile remains intact despite recent volatility. Jared Goff threw for 364 yards against Pittsburgh, and while efficiency dipped under pressure, the passing game still produced chunk plays at every level. With Amon-Ra St. Brown, Jameson Williams, and Jahmyr Gibbs all capable of stressing coverage horizontally and vertically, Detroit can dictate tempo early if it avoids negative plays.

Minnesota’s offense becomes far more limited with Brosmer under center. While he showed composure against the New York Giants, the game plan leaned heavily on quick throws and a controlled rushing attack. That approach becomes much harder against a Detroit defense that can load the box and force obvious passing situations. If the Vikings fall behind early, asking Brosmer to push the ball downfield consistently is a risky proposition.

Defensively, Minnesota has been competitive late in the season, but this matchup tests discipline more than raw effort. Detroit’s ability to sustain drives and wear down fronts creates problems for defenses that lack depth. On a short week, with travel and a backup quarterback involved, the Vikings are unlikely to match Detroit’s scoring pace unless turnovers swing the game. That points toward Detroit controlling both field position and time of possession.

Detroit Lions vs. Minnesota Vikings Predictions

Spread: Lions -6
Detroit’s offensive balance and quarterback stability create separation over four quarters.

Total: Under 44.5
Minnesota’s offensive ceiling drops sharply with Brosmer starting, limiting scoring upside.

Moneyline: Lions -275
Detroit is the more complete and reliable team in all phases.

Bet: Lions -6 (-110), Under 44.5 (-110), Lions ML (-275)

Denver Broncos vs. Kansas City Chiefs Odds

The Denver Broncos enter this matchup with everything still in front of them, while the Kansas City Chiefs are playing out the string after officially being eliminated from playoff contention. The quarterback situation for Kansas City is dire, with Chris Oladokun expected to start after consecutive ACL injuries to Patrick Mahomes and Gardner Minshew. That reality fundamentally changes how this game should be evaluated, as Kansas City is unlikely to generate consistent offense or sustain drives against a motivated Denver defense.

Denver’s defense is well-positioned to control this game from the opening snap. The Broncos have been particularly strong at limiting explosive plays and forcing long third downs, which becomes even more impactful against an inexperienced quarterback. Kansas City managed just nine points in its last game and struggled to protect the quarterback, a problem that could worsen against Denver’s pass rush. Short fields and defensive pressure should tilt time of possession heavily in Denver’s favor.

Offensively, the Denver Broncos do not need to be flashy to create separation. Bo Nix has shown enough efficiency to manage games when the defense sets the tone, and Denver’s rushing attack should find opportunities against a Kansas City front that has little left to play for. With Kansas City likely forced into conservative play-calling, Denver can gradually build a lead through field position and sustained drives rather than relying on explosive scoring.

The total is modest, and for good reason. Kansas City’s offense lacks upside with Oladokun under center, while Denver is unlikely to push the tempo unnecessarily. This sets up a game script where Denver controls the clock, limits possessions, and avoids mistakes. Unless Denver’s defense directly contributes points, this game profiles as one-sided but relatively low-scoring.

Denver Broncos vs. Kansas City Chiefs Predictions

Spread: Broncos -13.5
Denver’s defensive edge and quarterback stability should create consistent separation over four quarters.

Total: Under 36.5
Kansas City’s offensive limitations cap scoring potential on both sides.

Moneyline: Broncos -1050
Denver is the clearly superior and motivated team in every phase.

Bet: Broncos -13.5 (-108), Under 36.5 (-112), Broncos ML (-1050)

Houston Texans vs. Los Angeles Chargers Odds

The Houston Texans and Los Angeles Chargers meet in a Saturday matchup with real AFC playoff seeding implications, making this one of the more meaningful games on the Week 17 slate. Houston enters playing its best football of the season, while Los Angeles remains dangerous but inconsistent, particularly on defense. The Chargers’ offensive ceiling keeps them favored, but this matchup is far tighter than the spread suggests.

Houston’s defense continues to be the backbone of its late-season surge. The Texans have limited explosive plays and excelled at forcing opponents into long, methodical drives. That profile matters against a Chargers offense that prefers chunk plays through the air. If Houston can keep Justin Herbert from consistently pushing the ball downfield, it can shorten the game and keep pressure on Los Angeles to execute in the red zone.

Offensively, the Houston Texans have found enough balance to complement their defense. C.J. Stroud does not need to play hero ball when the running game and short passing attack stay on schedule. Houston’s ability to protect the football has been a key factor during its recent winning stretch, and avoiding turnovers is critical against a Chargers team that can capitalize quickly on mistakes.

The total sits just under 40, which reflects respect for both defenses but also acknowledges the quarterback talent on the field. While Houston may not want a shootout, Los Angeles has shown it can score in bursts, especially at home. This creates a narrow margin where both teams can reach the low 20s without the game becoming overly chaotic, keeping both the spread and total in play late.

Houston Texans vs. Los Angeles Chargers Predictions

Spread: Texans +1.5
Houston’s defensive consistency and ball control make them live in a one-score game.

Total: Over 39.5
Both offenses should find enough success to push this total past the key number.

Moneyline: Texans +105
Houston’s current form and defensive edge give them upset potential.

Bet: Texans +1.5 (-110), Over 39.5 (-110), Texans ML (+105)

Green Bay Packers vs. Baltimore Ravens Odds

The Green Bay Packers return home in a critical late-season matchup with postseason positioning still in play, facing a Baltimore Ravens team dealing with mounting uncertainty on offense. Green Bay has leaned into ball control and efficiency at Lambeau Field, limiting mistakes and dictating tempo with a balanced offensive approach. In controlled environments, the Packers have consistently forced opponents to play their game.

The Packers’ offensive structure has held up even when explosive plays aren’t abundant. Jordan Love has been protected well in recent weeks, and Green Bay’s ability to sustain drives has helped keep their defense fresh. That approach becomes more valuable against a Baltimore team that relies heavily on defensive pressure and creating negative plays rather than winning prolonged possessions.

For the Ravens, the margin tightens considerably on the road. When they’re unable to dictate pace early, Baltimore’s offense becomes more predictable, especially in games where they fall behind the chains. While the Ravens’ defense remains capable of generating pressure, that advantage diminishes when opponents stay disciplined and avoid obvious passing situations.

This matchup profiles as a field-position battle rather than a shootout. Both teams are comfortable slowing the game down, which magnifies execution, clock management, and red-zone efficiency. Green Bay’s ability to protect the football and control tempo gives them a subtle but meaningful edge in a game where points are likely at a premium.

Green Bay Packers vs. Baltimore Ravens Predictions

Spread: Packers -3
Home-field advantage and superior tempo control favor Green Bay over four quarters.

Total: Under 40.5
Both teams lean toward conservative game scripts, limiting scoring opportunities.

Moneyline: Packers -166
Green Bay holds the more stable offensive profile and situational edge.

Bet: Packers -3 (-110), Under 40.5 (-110), Packers ML (-166)

Seattle Seahawks vs. Carolina Panthers Odds

The Seattle Seahawks enter this matchup in full control of their destiny after the overtime win over the Los Angeles Rams, a result that now puts them firmly in the driver’s seat for the No. 1 seed in the NFC. That win was a clear example of Seattle’s defensive structure holding up under pressure, forcing sustained drives and limiting explosive plays even when the offense stalled at times. With postseason positioning on the line, Seattle’s approach is unlikely to loosen.

Defensively, the Seahawks continue to separate themselves by dictating game flow rather than chasing it. Opponents are being forced to string together long possessions, which increases the likelihood of negative plays, penalties, or turnovers. That profile plays particularly well against a Carolina Panthers offense that has struggled to generate quick scoring when trailing and has shown limited explosiveness outside of scripted situations.

The Carolina Panthers have competed hard in recent weeks, but the offensive ceiling remains capped, especially if they fall behind early. The Panthers have had difficulty sustaining drives against disciplined defenses, and asking them to match scores with a Seattle team that controls tempo is a tough ask. If Carolina is forced into obvious passing situations, the margin for error shrinks quickly.

From a game script standpoint, this sets up as a controlled Seattle win rather than a shootout. The Seahawks don’t need to push pace aggressively; they simply need to stay on schedule offensively and allow the defense to suffocate Carolina’s scoring chances. With Seattle doing most of the offensive work, the total reflects expectations of efficiency without chaos.

Seattle Seahawks vs. Carolina Panthers Predictions

Spread: Seahawks -7
Seattle’s defensive edge supports a touchdown cover over four quarters.

Total: Under 42.5
Carolina’s scoring limitations cap overall game upside.

Moneyline: Seahawks -375
Seattle controls the matchup and postseason implications sharpen focus.

Bet: Seahawks -7 (-110), Under 42.5 (-110), Seahawks ML (-375)

New England Patriots vs. New York Jets Odds

The New England Patriots come into this matchup playing their best offensive football of the season after a 28–24 road win over the Baltimore Ravens last week. Drake Maye threw for 380 yards and two touchdowns in that game, consistently pushing the ball downfield and keeping Baltimore’s defense under pressure. New England moved the ball efficiently through the air and showed an ability to close late, something that had been missing earlier in the year.

The New York Jets are trending in the opposite direction after a 29–6 loss to the New Orleans Saints last week. The Jets struggled to protect the quarterback, surrendering eight sacks, and managed just six points despite 35 pass attempts from Brady Cook. New York failed to generate explosive plays and repeatedly stalled in Saints territory, continuing a season-long pattern of offensive inconsistency.

This matchup heavily favors New England’s passing attack against a Jets defense that has been on the field far too often. Stefon Diggs caught nine passes for 138 yards against Baltimore last week, and Drake Maye showed the willingness to attack vertically when protection holds. Against a Jets team that struggled to slow Chris Olave and allowed sustained drives to New Orleans, New England should control tempo early.

Game script is the key variable here. If the Patriots build an early lead, New York will be forced into a pass-heavy approach behind an offensive line that just gave up eight sacks. That dynamic creates separation potential late, especially with New England showing confidence pushing the pace rather than sitting on leads.

New England Patriots vs. New York Jets Predictions

Spread: Patriots -13.5
New England’s offensive form and matchup edge support a multi-score win.

Total: Over 42.5
The Patriots can do most of the scoring themselves, and New York should contribute late against softer coverage.

Moneyline: Patriots -1100
There’s no realistic upset path given current form.

Bet: Patriots -13.5 (-108), Over 42.5 (-118), Patriots ML (-1100)

Cincinnati Bengals vs. Arizona Cardinals Odds

The Cincinnati Bengals are coming off a dominant 45–21 win over the Miami Dolphins last week, powered by an efficient and explosive performance from Joe Burrow. Burrow completed 25 of 32 passes for 309 yards and four touchdowns against Miami, consistently attacking downfield and converting scoring chances. Cincinnati scored on six of its first seven meaningful drives, putting the game out of reach early.

The Bengals’ passing game was balanced and efficient, with Ja’Marr Chase catching nine passes for 109 yards and Tee Higgins adding a touchdown reception. Cincinnati also got meaningful production from Chase Brown, who rushed for 66 yards and added two receiving touchdowns. That offensive balance allowed the Bengals to control pace without relying on a single player.

The Arizona Cardinals are coming off a 26–19 loss to the Atlanta Falcons last week. Jacoby Brissett completed 16 of 31 passes for 203 yards with one touchdown and one interception against Atlanta. Arizona moved the ball at times but struggled to sustain drives once the Falcons tightened coverage in the second half.

Arizona’s offense leaned on short passes and a committee rushing approach, with Michael Carter leading the team with 65 rushing yards. While the Cardinals were competitive early, defensive breakdowns and limited explosive plays allowed Atlanta to pull away. Against a Bengals offense operating at a much higher efficiency level, Arizona faces a difficult task keeping pace over four quarters.

Cincinnati Bengals vs. Arizona Cardinals Predictions

Spread: Bengals -7.5
Cincinnati’s offensive efficiency supports laying more than a touchdown.

Total: Under 52.5
Arizona’s limited scoring output lowers shootout potential.

Moneyline: Bengals -410
Cincinnati is clearly the more complete team.

Bet: Bengals -7.5 (-105), Under 52.5 (-105), Bengals ML (-410)

Cleveland Browns vs. Pittsburgh Steelers Odds

The Pittsburgh Steelers are coming off a 29–24 win over the Detroit Lions last week, a game defined by their dominance on the ground. Jaylen Warren rushed 14 times for 143 yards and two touchdowns against Detroit, consistently flipping field position and keeping Pittsburgh in favorable down-and-distance situations. That rushing efficiency allowed the Steelers to dictate tempo for most of the game.

Aaron Rodgers threw for 266 yards with one touchdown and no interceptions against the Lions, but the passing game functioned more as a complement than a focal point. Pittsburgh didn’t push the ball aggressively downfield, instead leaning on ball control and efficiency while converting key third downs. That approach limited mistakes and kept Detroit from generating momentum.

The Cleveland Browns are coming off a 23–20 loss to the Buffalo Bills last week, a game where offensive consistency was an issue. Shedeur Sanders completed 20 of 29 passes for 157 yards with one touchdown and two interceptions against Buffalo. Cleveland moved the ball at times but struggled to sustain drives once the field shortened.

Cleveland’s defense kept the game within reach, but the Browns’ offense failed to capitalize on scoring opportunities. In a matchup expected to be low scoring, Pittsburgh’s ability to control the run game and protect the football gives them a clear structural edge.

Cleveland Browns vs. Pittsburgh Steelers Predictions

Spread: Steelers -3
Pittsburgh’s rushing advantage supports laying the field goal.

Total: Under 33.5
Both offenses project to play conservatively in a grind-it-out game.

Moneyline: Steelers -185
Pittsburgh’s ball control and efficiency favor a straight-up win.

Bet: Steelers -3 (-115), Under 33.5 (-105), Steelers ML (-185)

Miami Dolphins vs. Tampa Bay Buccaneers Odds

The Miami Dolphins are coming off a 45–21 loss to the Cincinnati Bengals last week, a game that highlighted ongoing defensive issues. Quinn Ewers made another start for Miami and threw for 260 yards with two interceptions against Cincinnati. While Ewers was able to move the ball between the 20s, turnovers consistently halted momentum.

Miami did find some success on the ground, with De’Von Achane rushing for 81 yards and a touchdown against the Bengals. However, the Dolphins struggled to finish drives and were unable to keep pace once Cincinnati pulled ahead. That pattern has persisted when Miami falls behind early.

The Tampa Bay Buccaneers are coming off a 23–20 loss to the Carolina Panthers last week. Baker Mayfield threw for 145 yards with one touchdown and one interception, while Tampa Bay leaned heavily on the run game to stay competitive. The Buccaneers moved the ball effectively at times but failed to close out drives.

Tampa Bay’s defense held Carolina in check for much of the game, and that unit now faces a Miami offense still adjusting with Ewers under center. If the Buccaneers can limit turnovers and force Miami into obvious passing situations, they are positioned to control both tempo and field position.

Miami Dolphins vs. Tampa Bay Buccaneers Predictions

Spread: Buccaneers -5.5
Tampa Bay’s defensive edge and Miami’s turnover issues support the favorite.

Total: Under 45.5
Miami’s offensive inefficiency lowers overall scoring expectations.

Moneyline: Buccaneers -258
Tampa Bay is better equipped to win a controlled game.

Bet: Buccaneers -5.5 (-110), Under 45.5 (-110), Buccaneers ML (-258)

Jacksonville Jaguars vs. Indianapolis Colts Odds

The Jacksonville Jaguars enter Week 17 playing their most complete football of the season, with an offense that has found rhythm and balance. Trevor Lawrence is distributing the ball efficiently, and Jacksonville has been able to sustain drives while creating explosive plays when defenses overcommit to stopping the run. Staying ahead of the chains has allowed the Jaguars to control tempo and dictate game flow.

The Indianapolis Colts are limited offensively, especially with 44-year-old Philip Rivers making his third start of the season. While Rivers can still manage a game in short-yardage situations, the Colts struggle to generate explosive plays and consistently push the ball downfield. That puts pressure on Indianapolis to stay close early, as falling behind forces them into uncomfortable passing situations.

Jacksonville’s ability to score quickly creates a difficult matchup for a Colts team that prefers a slower, ball-control approach. If the Jaguars jump out to an early lead, Indianapolis is unlikely to keep pace over four quarters. That dynamic increases both Jacksonville’s spread appeal and the likelihood of points piling up.

The total reflects Jacksonville’s recent offensive production, and Indianapolis’ defense may have trouble slowing down a Jaguars unit playing with confidence and urgency.

Jacksonville Jaguars vs. Indianapolis Colts Predictions

Spread: Jaguars -6.5
Jacksonville’s offensive edge and ability to dictate tempo support separation.

Total: Over 48.5
The Jaguars’ scoring profile keeps the Over in play.

Moneyline: Jaguars -285
Jacksonville controls the matchup in all phases.

Bet: Jaguars -6.5 (-110), Over 48.5 (-110), Jaguars ML (-285)

New Orleans Saints vs. Tennessee Titans Odds

The New Orleans Saints offense showed improved rhythm last week against the Jets, with Tyler Shough throwing for 308 yards and a touchdown while consistently attacking intermediate zones. Chris Olave was the focal point of that effort, catching 10 passes for 148 yards and repeatedly flipping field position. When New Orleans is able to stay ahead of schedule, the offense looks far more cohesive.

The Tennessee Titans are still searching for consistency through the air, even after a respectable showing last week against the shorthanded Chiefs. Cam Ward threw for 228 yards and two touchdowns in that game, but Tennessee struggled to sustain drives once forced into obvious passing situations. Protection issues and stalled third downs prevented the Titans from fully capitalizing on early momentum.

Tony Pollard carried the load on the ground, rushing for 102 yards against Houston last week while helping keep the game close. However, Tennessee’s reliance on the run game becomes problematic if they fall behind, especially against a Saints defense that excels at forcing short completions and limiting yards after the catch.

This matchup sets up as a grind-heavy contest where execution matters more than explosiveness. New Orleans is comfortable winning games in the low 20s, while Tennessee has struggled to score efficiently when possessions are limited. That dynamic favors the Saints’ ability to control tempo and field position over four quarters.

New Orleans Saints vs. Tennessee Titans Predictions

Spread: Saints -2.5
New Orleans’ passing efficiency and defensive structure create a narrow edge.

Total: Under 39.5
Both teams prefer slower pace and longer drives.

Moneyline: Saints -148
New Orleans is the steadier side in a low-variance matchup.

Bet: Saints -2.5 (-110), Under 39.5 (-110), Saints ML (-148)

New York Giants vs. Las Vegas Raiders Odds

The New York Giants‘ offense is extremely limited through the air, a problem that was again exposed last week against the Vikings. Jaxson Dart completed just seven passes for 33 yards in that loss, and New York failed to generate a single explosive passing play. Protection issues forced the Giants into a conservative approach that made it difficult to sustain drives once they fell behind.

On the ground, Tyrone Tracy Jr. was the lone bright spot, rushing for 71 yards against the Vikings last week while showing good vision between the tackles. Even so, the Giants struggled to turn rushing success into points, finishing drives without consistency once they crossed midfield. That inefficiency has been a recurring issue whenever New York faces disciplined defenses.

The Las Vegas Raiders bring a much higher offensive ceiling into this matchup. Geno Smith threw for 201 yards and two touchdowns against the Texans last week, pushing the ball downfield efficiently while keeping the offense on schedule. The Raiders were able to score on chunk plays rather than relying solely on long drives, a key difference compared to New York’s approach.

Ashton Jeanty was a difference-maker despite the loss to Houston, rushing for 128 yards and a touchdown while also adding a 60-yard receiving score. His ability to impact the game both on the ground and through the air gives Las Vegas a versatility edge that New York simply doesn’t have. In a matchup expected to stay close, that offensive upside looms large.

New York Giants vs. Las Vegas Raiders Predictions

Spread: Raiders -1.5
Las Vegas’ explosive-play potential gives them the edge in a one-score game.

Total: Under 41.5
New York’s limited passing game caps overall scoring.

Moneyline: Raiders -115
Las Vegas has the more reliable offensive profile.

Bet: Raiders -1.5 (-110), Under 41.5 (-110), Raiders ML (-115)

Philadelphia Eagles vs. Buffalo Bills Odds

Buffalo comes into this matchup playing efficient, controlled football on both sides of the ball. Josh Allen threw for 130 yards on 12-of-19 passing last week against Cleveland, avoiding turnovers and letting the run game carry the offense. James Cook handled 16 carries for 117 yards and two touchdowns against the Browns, consistently setting Buffalo up in favorable down-and-distance situations.

Philadelphia’s offense remains capable but uneven. Jalen Hurts threw for 185 yards and️ and two touchdowns last week against Washington, but the Eagles leaned heavily on the ground game. Saquon Barkley ran for 132 yards on 21 carries against the Commanders, accounting for much of Philadelphia’s offensive stability. When the Eagles are forced into longer passing situations, drives have tended to stall.

Defensively, Buffalo continues to limit explosive plays and force opponents to earn points. The Bills allowed just 20 points to Cleveland last week, holding the Browns in check despite multiple short fields. Philadelphia’s defense has been solid but allowed Washington to move the ball early before settling in.

The total reflects expectations of a controlled, physical game rather than a track meet. Both teams prefer to establish the run and limit mistakes, which points toward longer possessions and fewer explosive scoring swings.

Philadelphia Eagles vs. Buffalo Bills Predictions

Spread: Bills -1.5
Buffalo’s consistency and ability to dictate tempo give them a narrow edge at home.

Total: Under 44.5
Both offenses lean on the run, and both defenses limit chunk plays.

Moneyline: Bills -118
Buffalo is the steadier side in a matchup likely decided late.

Bet: Bills -1.5 (-110), Under 44.5 (-110), Bills ML (-118)

Chicago Bears vs. San Francisco 49ers Odds

The San Francisco 49ers come into this matchup riding a dominant offensive showing last week against the Colts, putting up 48 points while controlling the game from start to finish. Brock Purdy threw for 295 yards and five touchdowns against Indianapolis, spreading the ball efficiently and consistently attacking downfield when matchups opened up. The 49ers scored in every quarter and never allowed the game to slow down, a reminder of how quickly this offense can bury opponents when it stays on schedule.

Christian McCaffrey continued to function as the engine of the offense last week, totaling 117 rushing yards on 21 carries against the Colts while also adding two receiving touchdowns. San Francisco’s ability to stay balanced showed up across the box score, with the team rushing for 145 yards and keeping Purdy clean for most of the afternoon. George Kittle also had a big impact through the air, catching seven passes for 115 yards and a touchdown, giving the Bears another matchup problem to account for in the middle of the field.

The Chicago Bears‘ most recent performance came in a thrilling OT win against Green Bay, where the Bears showed some offensive life but struggled to sustain it for four quarters. Caleb Williams threw for 186 yards and two touchdowns against the Packers, but Chicago was forced into catch-up mode early. The Bears leaned on D’Andre Swift and Kyle Monangai on the ground, combining for 120 rushing yards, though explosive plays were limited and drives stalled too often.

The contrast in offensive efficiency stands out entering this matchup. San Francisco just dismantled Indianapolis with explosive plays and red-zone execution, while Chicago needed short fields and isolated chunk gains to stay competitive against Green Bay. If the 49ers replicate anything close to last week’s offensive rhythm, Chicago will have to play from behind again, which plays directly into San Francisco’s strengths.

Chicago Bears vs. San Francisco 49ers Predictions

Spread: 49ers -3
San Francisco’s offensive performance against Indianapolis last week supports laying a short number.

Total: Over 52.5
The 49ers showed last week they can carry a total almost by themselves.

Moneyline: 49ers -162
San Francisco’s efficiency and balance give them the clear edge.

Bet: 49ers -3 (-110), Over 52.5 (-110), 49ers ML (-162)

Los Angeles Rams vs. Atlanta Falcons Odds

The Los Angeles Rams played one of the most explosive games of the season last week in a 38–37 overtime loss to the Seattle Seahawks. Matthew Stafford threw for 457 yards and three touchdowns, repeatedly pushing the ball downfield and keeping Los Angeles aggressive in all situations. Puka Nacua was the centerpiece of that attack, catching 12 passes for 225 yards and two touchdowns, while the Rams still managed 124 rushing yards despite trailing for long stretches.

The Atlanta Falcons come in off a 26–19 road win over the Arizona Cardinals, leaning on offensive balance rather than explosive passing volume. Kirk Cousins threw for 197 yards with two touchdowns, while Bijan Robinson and Tyler Allgeier combined for 155 rushing yards. Robinson also led Atlanta receivers with 92 receiving yards and a touchdown, giving the Falcons multiple ways to stay on schedule and control tempo.

Defensively, the matchup favors Los Angeles’ ability to force Atlanta out of its comfort zone. The Rams were shredded through the air last week, but that came against a pass-heavy Seattle offense. Atlanta’s offense is far more run-oriented, which plays into a Rams front that can rally to the ball and force longer third downs if they avoid early mistakes.

Game flow is the key variable. If the Rams strike early, Atlanta’s margin for error shrinks quickly. The Falcons are capable of sustaining drives, but they are not built to trade explosive possessions. With Stafford, Nacua, and a vertical passing game clicking, Los Angeles has a clear path to separating once pace increases.

Atlanta Falcons vs. Los Angeles Rams Predictions

Spread: Rams -7.5
Los Angeles’ offensive ceiling is significantly higher, especially if Atlanta is forced to chase points.

Total: Over 49.5
The Rams showed last week they can carry a total almost by themselves, and Atlanta can contribute enough to push this number over.

Moneyline: Rams -440
Los Angeles is the steadier side with far more ways to control the game.

Bet: Rams -7.5 (-110), Over 49.5 (-110), Rams ML (-440)

NFL Week 17 Best Bets

Here are our favorite NFL bets for Week 17:

• Cincinnati Bengals -7.5 vs. Arizona Cardinals (-105)
• Pittsburgh Steelers +3 vs. Cleveland Browns (-105)
• Tampa Bay Buccaneers -5.5 vs. Miami Dolphins (-110)

Cincinnati continues to look like one of the league’s most dangerous late-season offenses and now draws an Arizona defense that has struggled to generate stops. Joe Burrow threw for four touchdowns last week, and the Bengals consistently moved the ball through the air while still maintaining balance on the ground. Arizona allowed Atlanta to control tempo and possession, and that becomes a major problem against a Cincinnati offense capable of scoring quickly and efficiently. If the Bengals play clean football, this spread is well within reach.

Pittsburgh finds itself in a favorable spot as a short underdog in what profiles as a lower-scoring, physical AFC North game. The Steelers leaned heavily on the run last week and played from ahead for long stretches, while their defense limited explosive plays and kept Detroit from pulling away. Cleveland’s offense has been inconsistent sustaining drives, and that keeps the door open for Pittsburgh to stay within a field goal throughout. In a game that projects to come down to late possessions, grabbing the points offers value.

Tampa Bay draws a Miami team making another start with Quinn Ewers under center. The Dolphins showed flashes offensively last week but struggled to protect the football and finish drives. Tampa’s offense has been uneven, yet the Buccaneers still generate enough pressure and field position advantages to separate. Against a Miami team with a limited margin for error, Tampa Bay is in position to cover a mid-range number.

If you roll these three favorites into an NFL parlay, the combined odds should land in the +600 range, depending on where you shop. A $100 wager would return roughly $600. As always, compare prices across your sportsbook accounts and consider pairing these plays with your favorite College Football parlays for additional value.