ABC will broadcast this week 17 NFC matchup between the Lions and 49ers, which is set to kick off at 8:15 ET. The Lions are favored on the road with a point spread of -3.5 and a money line of -196. The 49ers, the home team, have a money line of +164, and the over/under line is at 50.5 points. The game is being played at Levi’s Stadium in Santa Clara, CA. At 13-2, the Lions hold the top spot in our power rankings and have a 76.3% chance of winning the NFC North. They bounced back from a week 15 loss to the Bills with a 34-17 win over the Bears in week 16, covering the 6.5-point spread. The

The Greyhounds and Blue Demons are set to face off at 2:00 ET on FS1. The Blue Demons will host the game at Wintrust Arena in Chicago, IL. The over/under line for this matchup is currently at 146.5 points, and DePaul is favored by -16.5 at home against Loyola Maryland. Loyola Maryland dropped to 4-5 on the season after a 76-68 home loss to Hampton on Saturday. The Greyhounds, who were -2 favorites going into the game, failed to cover the spread. After trailing 32-26 at halftime, Loyola Maryland scored 42 points in the 2nd half but allowed 44 points. The total points for the game ended at 144, surpassing the O/U line of 137.5. Milos Ilic and Wayne Bristol

Coming off back-to-back stellar shooting performances, Louisville has the chance to match last season’s win total when they host Eastern Kentucky (EKU) this Saturday afternoon. The Cardinals (7-5) have caught fire from beyond the arc, making a combined 29 three-pointers in their last two games. After sinking 14 threes in a hard-fought loss to then-No. 5 Kentucky on Dec. 14, Louisville upped the ante by hitting 15 of 29 triples in a decisive 90-76 win over Florida State on Dec. 21. Reyne Smith was electric off the bench against Florida State, draining six treys, while Terrence Edwards showcased his long-range talent with five three-pointers in the loss to Kentucky. “We played with great poise,” head coach Pat Kelsey said after

The Missouri Tigers are the -2.5 point favorites as they take on the Iowa Hawkeyes in the TransPerfect Music City Bowl. Kick-off is set for 2:30 ET from Nissan Stadium in Nashville, with ESPN handling the broadcast. The over/under line is at 43.5 points. Iowa comes in with an 8-4 record, while Missouri is 9-3 on the season. Iowa enters Week 1 against Missouri with an 8-4 record. They’ve gone 5-1 at home but are 2-3 on the road. The Hawkeyes have been favored in 10 of their 12 games, going 7-3 as the favorite. Iowa’s over/under record is 8-3, with their games averaging 45.1 points. This week’s line is 43.5, and their average over/under line has been 40.2 points.