The Jaguars and Texans will kick off at 1:00 ET on Sunday, September 29th at NRG Stadium in Houston. The Texans are the heavy favorite with a money line of -313, and they are favored by -7 on the point spread. This week four AFC South matchup is being televised on CBS, with the over/under line set at 45.5 points. Jacksonville vs. Houston Key Information Teams: Jaguars at Texans Where: NRG Stadium Houston Date: Sunday, September 29th Betting Odds HOU -313 | JAX +250 O/U 45.5 The Jaguars Can Win If... The Jaguars are still looking for their first win of the season after getting blown out 47-10 by the Bills in their most recent game. Jacksonville's record is now 0-3 after the loss.

The Browns and Raiders are set to kick off at 4:25 ET on Sunday, September 29th at Allegiant Stadium in Las Vegas. The Raiders are the slight favorite with a point spread of -1. On the money line, the Raiders are -114, and the Browns are -106. The over/under line is currently at 37 points. This week four AFC matchup is being televised on CBS. Cleveland vs. Las Vegas Key Information Teams: Browns at Raiders Where: Allegiant Stadium Las Vegas Date: Sunday, September 29th Betting Odds LV -114 | CLE -106 O/U 37 The Browns Can Win If... The Browns are now 1-2 after losing to the Giants 21-15 in their most recent game. Cleveland was favored by -6.5 at home but lost straight-up

From Progressive Field in Cleveland, we have the Astros and Guardians facing off in an AL matchup. First pitch for this one is set for 7:10 PM ET. MLBN is carrying this one on TV. The forecast for Friday's matchup calls for cloudy skies and temperatures in the mid-70s. Ronel Blanco is starting for the Astros, and they are 1st in the AL West. The Guardians are starting Joey Cantillo and they are favored at -122 on the money line. The Astros' money line odds are at +103. Today's over/under line is sitting at 7.5 runs. Houston vs. Cleveland Key Information Teams: Astros at Guardians Where: Progressive Field Cleveland Date: Friday, September 27th Betting Odds CLE -122 | HOU +103 O/U 7.5 The Astros

At 6:45 PM ET, the Phillies and Nationals face off in an NL East matchup. This one is being played at Nationals Park in Washington, DC. The Phillies are the heavy favorite on the money line, with their odds sitting at -185 compared to the Nationals at +155. The over/under line is currently at 8 runs. Philadelphia has a record of 94-65, while the Nationals are 69-90. Trevor Williams is starting for the Nationals, and they are looking to snap a four-game losing streak. The Phillies are starting Ranger Suarez. NSPPH is carrying the game on TV. Philadelphia vs. Washington Key Information Teams: Phillies at Nationals Where: Nationals Park Washington Date: Friday, September 27th Betting Odds PHI -185 | WSH +155 O/U 8 The