The St. Andrews University Eagles are the athletic teams for St. Andrews University in Laurinburg, North Carolina. The university is a member of the National Association of Intercollegiate Athletics (NAIA), primarily competing in Appalachian Athletic Conference. The Knights also compete in the Mid-South Conference for wrestling and swimming.

St. Andrews was formerly a member of the National Collegiate Athletic Association (NCAA) at the Division II level, primarily competing in Conference Carolinas from 1988 to 2012. The university transitioned to the NAIA after 23 years in the NCAA, following the end of the 2011-12 academic year.